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Leigh Johnston

Explore the profile of Leigh Johnston including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 349
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Recent Articles
1.
Sekwadi P, Smith A, Maruma W, Mongologa G, Tsele G, Ngomane M, et al.
Open Forum Infect Dis . 2024 Mar; 11(3):ofae118. PMID: 38505295
Background: In South Africa, the annual incidence of enteric fever averaged 0.1 per 100 000 persons between 2003 and 2018. During 2021 an increase in the number of enteric fever...
2.
Ordidge R, Blunck Y, Glarin R, Moffat B, Johnston L
NMR Biomed . 2021 Dec; 35(6):e4672. PMID: 34970797
Great attention is being paid to solving, or mitigating, the technical problems associated with MRI at ultrahigh field strengths of 7 T and higher. This paper explores the use of...
3.
Rana S, Shishegar R, Quezada S, Johnston L, Walker D, Tolcos M
Cereb Cortex . 2019 Feb; 29(11):4697-4708. PMID: 30721930
In many species of Mammalia, the surface of the brain develops from a smooth structure to one with many fissures and folds, allowing for vast expansion of the surface area...
4.
Immonen R, Smith G, Brady R, Wright D, Johnston L, Harris N, et al.
Epilepsy Res . 2019 Jan; 150:46-57. PMID: 30641351
Preclinical imaging studies of posttraumatic epileptogenesis (PTE) have largely been proof-of-concept studies with limited animal numbers, and thus lack the statistical power for biomarker discovery. Epilepsy Bioinformatics Study for Antiepileptogenic...
5.
Immonen R, Harris N, Wright D, Johnston L, Manninen E, Smith G, et al.
Neurobiol Dis . 2018 Oct; 123:75-85. PMID: 30321600
Posttraumatic epilepsy (PTE) is a major neurodegenerative disease accounting for 20% of symptomatic epilepsy cases. A long latent phase offers a potential window for prophylactic treatment strategies to prevent epilepsy...
6.
Kottaram A, Johnston L, Ganella E, Pantelis C, Kotagiri R, Zalesky A
Hum Brain Mapp . 2018 May; 39(9):3663-3681. PMID: 29749660
Correlation in functional MRI activity between spatially separated brain regions can fluctuate dynamically when an individual is at rest. These dynamics are typically characterized temporally by measuring fluctuations in functional...
7.
Karve I, Zhang M, Habgood M, Frugier T, Brody K, Sashindranath M, et al.
eNeuro . 2016 Mar; 3(1). PMID: 27022620
Type-1 interferons (IFNs) are pleiotropic cytokines that signal through the type-1 IFN receptor (IFNAR1). Recent literature has implicated the type-1 IFNs in disorders of the CNS. In this study, we...
8.
Shultz S, Tan X, Wright D, Liu S, Semple B, Johnston L, et al.
J Neurotrauma . 2014 Jan; 31(10):976-83. PMID: 24392832
Traumatic brain injury (TBI) is an international health concern with a complex pathogenesis resulting in major long-term neurological, neurocognitive, and neuropsychiatric outcomes. Although neuroinflammation has been identified as an important...
9.
Kolbe S, Bajraszewski C, Chapman C, Nguyen T, Mitchell P, Paine M, et al.
Hum Brain Mapp . 2011 Sep; 33(9):2047-61. PMID: 21915943
Trans-synaptic degeneration could exacerbate neurodegeneration in multiple sclerosis (MS). We aimed to assess whether anterograde trans-synaptic degeneration could be identified in the primary visual pathway in vivo. Diffusion tensor imaging...
10.
Bohanna I, Georgiou-Karistianis N, Sritharan A, Asadi H, Johnston L, Churchyard A, et al.
Brain Imaging Behav . 2011 Mar; 5(3):171-80. PMID: 21437574
White matter (WM) degeneration is an important feature of Huntington's disease (HD) neuropathology. To investigate WM degeneration we used Diffusion Tensor Imaging and Tract-Based Spatial Statistics to compare Fractional Anisotropy,...