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Leif Matthiesen

Explore the profile of Leif Matthiesen including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 659
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Recent Articles
1.
Roepke E, Hellgren M, Hjertberg R, Blomqvist L, Matthiesen L, Henic E, et al.
Acta Obstet Gynecol Scand . 2018 Apr; 97(8):921-941. PMID: 29603135
Introduction: Medical treatment of women with idiopathic recurrent pregnancy loss is controversial. The objective was to assess the effects of different treatments on live birth rates and complications in women...
2.
Abelius M, Jedenfalk M, Ernerudh J, Janefjord C, Berg G, Matthiesen L, et al.
Pediatr Allergy Immunol . 2017 Sep; 28(8):818-824. PMID: 28892576
Background: The immunological environment during pregnancy may differ between allergic and non-allergic women. This study investigates the effect of maternal allergy on the allergen-induced cytokine and chemokine levels and whether...
3.
Roepke E, Matthiesen L, Rylance R, Christiansen O
Acta Obstet Gynecol Scand . 2017 Aug; 96(11):1365-1372. PMID: 28832895
Introduction: The aim of this study was to estimate the incidence of recurrent pregnancy loss (RPL). The prevalence of RPL defined as three or more consecutive miscarriages before gestation week...
4.
Boij R, Mjosberg J, Svensson-Arvelund J, Hjorth M, Berg G, Matthiesen L, et al.
Am J Reprod Immunol . 2015 Jun; 74(4):368-78. PMID: 26118401
Problem: A deficiency in regulatory T (Treg) cells causing reduced immune regulatory capacity has been proposed in preeclampsia. Objective: Utilizing recent advances in flow cytometry phenotyping, we aimed to assess...
5.
Abelius M, Janefjord C, Ernerudh J, Berg G, Matthiesen L, Duchen K, et al.
Am J Reprod Immunol . 2014 Dec; 73(5):445-59. PMID: 25491384
Problem: How maternal allergy affects the systemic and local immunological environment during pregnancy and the immune development of the offspring is unclear. Method Of Study: Expression of 40 genes was...
6.
Abelius M, Lempinen E, Lindblad K, Ernerudh J, Berg G, Matthiesen L, et al.
Pediatr Allergy Immunol . 2014 Jun; 25(4):387-93. PMID: 24953298
Background: The influence of the intra-uterine environment on the immunity and allergy development in the offspring is unclear. We aimed to investigate (i) whether the pregnancy magnifies the Th2 immunity...
7.
Persson M, Ekerfelt C, Ernerudh J, Matthiesen L, Abelius M, Jonsson Y, et al.
J Reprod Immunol . 2012 Jul; 95(1-2):50-8. PMID: 22784413
Normal pregnancy and allergy are both characterized by a T helper (Th) 2 deviation. In the current study, we hypothesized that paternal antigen-induced cytokine responses during pregnancy would be deviated...
8.
Boij R, Svensson J, Nilsson-Ekdahl K, Sandholm K, Lindahl T, Palonek E, et al.
Am J Reprod Immunol . 2012 May; 68(3):258-70. PMID: 22626009
Problem: Although preeclampsia has been associated with inflammation, coagulation, and angiogenesis, their correlation and relative contribution are unknown. Method Of Study: About 114 women with preeclampsia, 31 with early onset...
9.
Matthiesen L, Kalkunte S, Sharma S
Am J Reprod Immunol . 2012 Mar; 67(4):334-40. PMID: 22380628
Recurrent spontaneous abortion (RSA), three or more pregnancy losses prior to 20 weeks, occurs in about 1% of all pregnancies, 50% of RSA cases remain unexplained and unresolved. Recently, immune...
10.
Abelius M, Ernerudh J, Berg G, Matthiesen L, Nilsson L, Jenmalm M
Pediatr Res . 2011 Jul; 70(5):495-500. PMID: 21796021
Exposure to a strong T-helper 2 (Th2)-like environment during fetal development may promote allergy development. Increased cord blood (CB) levels of the Th2-associated chemokine CCL22 were associated with allergy development...