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Leif Breum

Explore the profile of Leif Breum including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 181
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Recent Articles
1.
Larsen R, Jarden M, Minet L, Frolund U, Hermann A, Breum L, et al.
Eur J Haematol . 2024 May; 113(3):298-309. PMID: 38717071
Reduced physical function caused by bone destruction, pain, anemia, infections, and weight loss is common in multiple myeloma (MM). Myeloma bone disease challenges physical exercise. Knowledge on the effects and...
2.
Olsen M, Almdal T, Madsbad S, Ovesen C, Gluud C, Sneppen S, et al.
Contemp Clin Trials Commun . 2023 Mar; 33:101095. PMID: 36923108
Background: The evidence on the effects of metformin and insulin in type 2 diabetes patients on quality of life, patient satisfaction, and cardiovascular outcomes is unclear. Methods: The Copenhagen Insulin...
3.
Larsen E, Kjaer L, Lundby-Christensen L, Boesgaard T, Breum L, Gluud C, et al.
Free Radic Biol Med . 2021 Nov; 178:18-25. PMID: 34823018
Formation of reactive oxygen species has been linked to the development of diabetes complications. Treatment with metformin has been associated with a lower risk of developing diabetes complications, including when...
4.
Winckler K, Thorsteinsson B, Wiinberg N, Jensen A, Lundby-Christensen L, Heitmann B, et al.
J Diabetes Complications . 2020 Aug; 34(10):107681. PMID: 32741659
Aims: To investigate measures of carotid intima-media thickness (IMT) and conventional cardiovascular (CV) risk factors as predictors of future carotid IMT, and the prediction of CV events during follow-up based...
5.
Nordklint A, Almdal T, Vestergaard P, Lundby-Christensen L, Jorgensen N, Boesgaard T, et al.
Calcif Tissue Int . 2020 May; 107(2):160-169. PMID: 32468187
Preclinical studies have shown a potential osteoanabolic effect of metformin but human studies of how metformin affects bone turnover are few. A post hoc sub-study analysis of an 18-month multicenter,...
6.
Lundby-Christensen L, Vaag A, Tarnow L, Almdal T, Lund S, Wetterslev J, et al.
BMJ Open . 2016 Feb; 6(2):e008377. PMID: 26916685
Objective: To assess the effect of 3 insulin analogue regimens on change in carotid intima-media thickness (IMT) in patients with type 2 diabetes. Design And Setting: Investigator-initiated, randomised, placebo-controlled trial...
7.
Lundby-Christensen L, Tarnow L, Boesgaard T, Lund S, Wiinberg N, Perrild H, et al.
BMJ Open . 2016 Feb; 6(2):e008376. PMID: 26916684
Objective: To assess the effect of metformin versus placebo both in combination with insulin analogue treatment on changes in carotid intima-media thickness (IMT) in patients with type 2 diabetes. Design...
8.
Astrup A, Madsbad S, Breum L, Jensen T, Kroustrup J, Larsen T
Lancet . 2013 Jul; 382(9887):127. PMID: 23849924
No abstract available.
9.
Holm J, Breum L, Stenfeldt K, Hitz M
Case Rep Endocrinol . 2012 Sep; 2012:638298. PMID: 22988530
Lymphoma may occasionally involve the adrenal glands, but primary adrenal lymphoma (PAL) is very rare and only few cases have been reported. We present a case of a 60-year-old, otherwise...
10.
Vinberg M, Madsen M, Breum L, Kessing L, Fink-Jensen A
Nord J Psychiatry . 2011 Jul; 66(2):142-5. PMID: 21770840
Background: Patients with affective disorder have higher mortality not only because of their affective illness but also because of a higher risk of death from physical illness especially cardiovascular diseases....