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Leen Antonio

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Articles 62
Citations 725
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Recent Articles
1.
Narinx N, Nyamaah J, David K, Sommers V, Walravens J, Fiers T, et al.
Clin Chem Lab Med . 2025 Mar; PMID: 40068942
Objectives: To compare clinical laboratory workflows for the assessment of androgens in men, focusing on total testosterone (T), sex hormone-binding globulin (SHBG) and free T, in clinical laboratories throughout Europe....
2.
Strubbe M, David K, Peene B, Eeckhout B, Van der Schueren B, Decallonne B, et al.
Rev Endocr Metab Disord . 2024 Dec; 26(1):125-135. PMID: 39648248
Intravenous iron supplementation is increasingly used to safely and effectively correct iron deficiency anemia, but some formulations are linked to a renal phosphate wasting syndrome which is mediated by fibroblast...
3.
Narinx N, Marriott R, Murray K, Adams R, Ballantyne C, Bauer D, et al.
Eur J Endocrinol . 2024 Nov; 191(5):523-534. PMID: 39575586
Objective: Sociodemographic, lifestyle, and medical variables influence total testosterone (T) and sex hormone-binding globulin (SHBG) concentrations. The relationship between these factors and "free" T remains unclear. We examined 21 sociodemographic,...
4.
Nyamaah J, Narinx N, Antonio L, Vanderschueren D
Curr Opin Endocrinol Diabetes Obes . 2024 Oct; 31(6):230-235. PMID: 39445719
Purpose Of Review: Due to technical requirements and high cost, equilibrium dialysis-free testosterone (T) measurements are not commonly available in clinical practice. Clinicians rely on calculated free T (cFT) as...
5.
Rochtus A, Asscherickx W, Timmers M, Vermeer S, Antonio L
JCEM Case Rep . 2024 Oct; 2(11):luae195. PMID: 39444518
Biallelic pathogenic variants in cause a syndrome characterized by hypogonadotropic hypogonadism, cerebellar ataxia, chorea, and cognitive impairment, a combination first described as Gordon Holmes syndrome (MIM 212840). We report 2...
6.
de Silva N, Papanikolaou N, Grossmann M, Antonio L, Quinton R, Anawalt B, et al.
Lancet Diabetes Endocrinol . 2024 Aug; 12(10):761-774. PMID: 39159641
Organic male hypogonadism due to irreversible hypothalamic-pituitary-testicular (HPT) pathology is easily diagnosed and treated with testosterone-replacement therapy. However, controversy surrounds the global practice of prescribing testosterone to symptomatic men with...
7.
Aerts A, Temmerman A, Vanhie A, Vanderschueren D, Antonio L
Sports Med Open . 2024 Jun; 10(1):72. PMID: 38861008
Background: Endurance exercise has the potential to affect reproductive function, with amenorrhea in female athletes. However, most studies focus on women. Evidence on the association between endurance exercise and male...
8.
Han T, Antonio L, Bartfai G, ONeill T, Punab M, Rastrelli G, et al.
Rev Endocr Metab Disord . 2024 Jun; 25(6):1097-1107. PMID: 38829475
Empirical evidence for a low normal or reference interval for serum prolactin (PRL) is lacking for men, while the implications of very low PRL levels for human health have never...
9.
Yeap B, Marriott R, Dwivedi G, Adams R, Antonio L, Ballantyne C, et al.
Ann Intern Med . 2024 May; 177(6):768-781. PMID: 38739921
Background: Whether circulating sex hormones modulate mortality and cardiovascular disease (CVD) risk in aging men is controversial. Purpose: To clarify associations of sex hormones with these outcomes. Data Sources: Systematic...
10.
Anand-Ivell R, Heng K, Antonio L, Bartfai G, Casanueva F, Maggi M, et al.
Aging Male . 2024 Apr; 27(1):2346322. PMID: 38676285
Insulin-like peptide 3 (INSL3) is a circulating biomarker for Leydig cell functional capacity in men, also indicating Leydig Cell Insufficiency (LCI) and potential primary hypogonadism. Using results from large cohort...