Lee Sael
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Explore the profile of Lee Sael including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
504
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Recent Articles
1.
Jeon H, Ahn J, Na B, Hong S, Sael L, Kim S, et al.
Exp Mol Med
. 2025 Jan;
57(1):284.
PMID: 39875568
No abstract available.
2.
Ham K, Sael L
Bioinformatics
. 2023 Oct;
39(10).
PMID: 37847785
Motivation: The usefulness of supervised molecular property prediction (MPP) is well-recognized in many applications. However, the insufficiency and the imbalance of labeled data make the learning problem difficult. Moreover, the...
3.
Jeon H, Ahn J, Na B, Hong S, Sael L, Kim S, et al.
Exp Mol Med
. 2023 Jul;
55(8):1734-1742.
PMID: 37524869
The detection of somatic DNA variants in tumor samples with low tumor purity or sequencing depth remains a daunting challenge despite numerous attempts to address this problem. In this study,...
4.
Park J, Lee D, Lee J, Gim J, Gunasekaran T, Choi K, et al.
Transl Psychiatry
. 2021 Nov;
11(1):590.
PMID: 34785643
Established genetic risk factors for Alzheimer's disease (AD) account for only a portion of AD heritability. The aim of this study was to identify novel associations between genetic variants and...
5.
Choi Y, Ohn J, Kim N, Kim W, Park K, Won S, et al.
PLoS One
. 2020 Jul;
15(7):e0236197.
PMID: 32701958
Genome-wide association studies of gastric cancer (GC) cases have revealed common gastric cancer susceptibility loci with low effect size. We investigated rare variants with high effect size via whole-exome sequencing...
6.
Lim Y, Yu I, Seo D, Kang U, Sael L
BMC Bioinformatics
. 2019 Jul;
20(Suppl 13):381.
PMID: 31337329
Background: How can we obtain fast and high-quality clusters in genome scale bio-networks? Graph clustering is a powerful tool applied on bio-networks to solve various biological problems such as protein...
7.
Dehiya V, Thomas J, Sael L
PLoS One
. 2018 Sep;
13(9):e0204101.
PMID: 30265692
Can structural information of proteins generate essential features for predicting the deleterious effect of a single nucleotide variant (SNV) independent of the known existence of the SNV in diseases? In...
8.
Lee J, Choi D, Sael L
PLoS One
. 2018 Jul;
13(7):e0200579.
PMID: 30044837
How can we find patterns and anomalies in a tensor, i.e., multi-dimensional array, in an efficient and directly interpretable way? How can we do this in an online environment, where...
9.
10.
Lee J, Oh S, Sael L
Bioinformatics
. 2018 Jun;
34(24):4151-4158.
PMID: 29931238
Motivation: Given multi-platform genome data with prior knowledge of functional gene sets, how can we extract interpretable latent relationships between patients and genes? More specifically, how can we devise a...