Lee R Machado
Overview
Explore the profile of Lee R Machado including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
320
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0
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Recent Articles
1.
Hameed A, Ketley J, Woodacre A, Machado L, Marsden G
PLoS One
. 2022 Mar;
17(3):e0265585.
PMID: 35358234
The extensive genetic variation in the lipooligosaccharide (LOS) core biosynthesis gene cluster has led to the development of a classification system; with 8 classes (I-VIII) for Campylobacter coli (C. coli)...
2.
Naidoo M, Jones L, Conboy B, Hamarneh W, DSouza D, Anthony K, et al.
Sci Rep
. 2022 Feb;
12(1):3200.
PMID: 35217778
Alterations in the expression of the Duchenne muscular dystrophy (DMD) gene have been associated with the development, progression and survival outcomes of numerous cancers including tumours of the central nervous...
3.
Al-Rayahi I, Machado L, Stover C
Medicina (Kaunas)
. 2021 Jan;
57(2).
PMID: 33494138
: Tumours are often low immunogenic. The role of complement, an innate immune defence system, in tumour control has begun to be elucidated, but findings are conflicting. A role for...
4.
Jones L, Naidoo M, Machado L, Anthony K
Cell Oncol (Dordr)
. 2020 Nov;
44(1):19-32.
PMID: 33188621
Background: Mutation of the Duchenne muscular dystrophy (DMD) gene causes Duchenne and Becker muscular dystrophy, degenerative neuromuscular disorders that primarily affect voluntary muscles. However, increasing evidence implicates DMD in the...
5.
Hameed A, Woodacre A, Machado L, Marsden G
Front Microbiol
. 2020 Jun;
11:677.
PMID: 32508756
Lipooligosaccharide (LOS) is an integral component of the cell membrane with a structure of core oligosaccharides forming inner and outer core regions and a lipid A moiety. The gene content...
6.
Machado L, Moseley P, Moss R, Deen S, Nolan C, Spendlove I, et al.
Oncotarget
. 2017 Dec;
8(60):101215-101223.
PMID: 29254158
High-mobility group protein B1 (HMGB1) has been implicated in numerous tumour types where expression regulates tumour cell growth and survival. We hypothesised that high HMGB1 expression in ovarian tumours would...
7.
Zuccherato L, Schneider S, Tarazona-Santos E, Hardwick R, Berg D, Bogle H, et al.
J R Soc Interface
. 2017 Mar;
14(128).
PMID: 28356540
While multiallelic copy number variation (mCNV) loci are a major component of genomic variation, quantifying the individual copy number of a locus and defining genotypes is challenging. Few methods exist...
8.
Rahbari R, Zuccherato L, Tischler G, Chihota B, Ozturk H, Saleem S, et al.
Hum Mutat
. 2016 Dec;
38(4):390-399.
PMID: 27995740
Fcγ receptors are a family of cell-surface receptors that are expressed by a host of different innate and adaptive immune cells, and mediate inflammatory responses by binding the Fc portion...
9.
Hargreaves C, Iriyama C, Rose-Zerilli M, Nagelkerke S, Hussain K, Ganderton R, et al.
PLoS One
. 2016 Mar;
11(3):e0145040.
PMID: 27007921
No abstract available.
10.
Hargreaves C, Iriyama C, Rose-Zerilli M, Nagelkerke S, Hussain K, Ganderton R, et al.
PLoS One
. 2015 Nov;
10(11):e0142379.
PMID: 26545243
Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (FcγRs). The low-affinity FcγR genes are highly homologous, map to...