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Lee Machado

Explore the profile of Lee Machado including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 375
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Recent Articles
1.
Antrobus M, Desai T, Young D, Machado L, Ribbans W, El Khoury L, et al.
Gene . 2024 Nov; 935:149046. PMID: 39490707
Background: Concussion is the most common neurological disorder affecting millions of people globally each year. Identifying epigenetic mechanisms influencing concussion incidence, severity and recovery could provide diagnostic and prognostic insight...
2.
Patel P, Ottensmeier C, Mulatero C, Lorigan P, Plummer R, Pandha H, et al.
Oncoimmunology . 2018 Jun; 7(6):e1433516. PMID: 29872563
A DNA vaccine, SCIB1, incorporating two CD8 and two CD4 epitopes from TRP-2/gp100 was evaluated in patients with metastatic melanoma. Each patient received SCIB1 via intramuscular injection with electroporation. The...
3.
Russell L, Capasso M, Vater I, Akasaka T, Bernard O, Calasanz M, et al.
Blood . 2009 Jul; 114(13):2688-98. PMID: 19641190
We report 2 novel, cryptic chromosomal abnormalities in precursor B-cell acute lymphoblastic leukemia (BCP-ALL): a translocation, either t(X;14)(p22;q32) or t(Y;14)(p11;q32), in 33 patients and an interstitial deletion, either del(X)(p22.33p22.33) or...
4.
Palendira U, Chinn R, Raza W, Piper K, Pratt G, Machado L, et al.
Blood . 2008 Jul; 112(8):3293-302. PMID: 18635810
The bone marrow plays a unique role within the immune system. We compared the phenotype and function of virus-specific CD8(+) T cells from matched samples of human peripheral blood and...
5.
Baumforth K, Birgersdotter A, Reynolds G, Wei W, Kapatai G, Flavell J, et al.
Am J Pathol . 2008 May; 173(1):195-204. PMID: 18502823
In approximately 50% of patients with Hodgkin's lymphoma (HL), the Epstein-Barr virus (EBV), an oncogenic herpesvirus, is present in tumor cells. After microarray profiling of both HL tumors and cell...
6.
Machado L, Jarrett R, Morgan S, Murray P, Hunter B, Hamilton E, et al.
Cancer Immunol Immunother . 2008 May; 58(1):85-94. PMID: 18488221
Circulating T lymphocytes enter a tissue if they express appropriate chemokine receptors and adhesion molecules to engage ligands presented at this site. To aid rational development of T cell-based therapies...