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Leanne J Cooper

Explore the profile of Leanne J Cooper including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 960
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Recent Articles
1.
Nakamura T, Kelly J, Trevisan J, Cooper L, Bentley A, Carmichael P, et al.
Mol Vis . 2010 Jun; 16:359-68. PMID: 20520745
Purpose: Synchrotron-based radiation (SRS) Fourier-transform infrared (FTIR) microspectroscopy potentially provides novel biomarkers of the cell differentiation process. Because such imaging gives a "biochemical-cell fingerprint" through a cell-sized aperture, we set...
2.
Matharu B, Gibson G, Parsons R, Huckerby T, Moore S, Cooper L, et al.
J Neurol Sci . 2009 Mar; 280(1-2):49-58. PMID: 19249060
The ability of galantamine (Reminyl) to inhibit the aggregation and toxicity of the beta-amyloid peptide (Abeta) was investigated. Galantamine showed concentration-dependent inhibition of aggregation of both Abeta 1-40 and Abeta...
3.
Koizumi N, Sakamoto Y, Okumura N, Tsuchiya H, Torii R, Cooper L, et al.
Cornea . 2008 Oct; 27 Suppl 1:S48-55. PMID: 18813075
Purpose: To review our attempt to devise a method of cultivated corneal endothelial transplantation using primates in which corneal endothelium, like that of humans, has low proliferative ability. Methods: Monkey...
4.
Nakamura T, Ohtsuka T, Sekiyama E, Cooper L, Kokubu H, Fullwood N, et al.
Stem Cells . 2008 Feb; 26(5):1265-74. PMID: 18292208
Hes1, a major target gene in Notch signaling, regulates the fate and differentiation of various cell types in many developmental systems. To gain a novel insight into the role of...
5.
Koizumi N, Sakamoto Y, Okumura N, Okahara N, Tsuchiya H, Torii R, et al.
Invest Ophthalmol Vis Sci . 2007 Sep; 48(10):4519-26. PMID: 17898273
Purpose: To examine the feasibility of cultivated corneal endothelial cell transplantation in a primate model. Methods: Monkey corneal endothelial cells (MCECs) obtained from three cynomolgus monkeys were cultivated, with subcultures...
6.
Masad A, Hayes L, Tabner B, Turnbull S, Cooper L, Fullwood N, et al.
FEBS Lett . 2007 Jul; 581(18):3489-93. PMID: 17617411
Amyloid deposits derived from the amylin peptide accumulate within pancreatic islet beta-cells in most cases of type-2 diabetes mellitus (T2Dm). Human amylin 'oligomers' are toxic to these cells. Using two...
7.
Sekiyama E, Nakamura T, Kurihara E, Cooper L, Fullwood N, Takaoka M, et al.
Invest Ophthalmol Vis Sci . 2007 Mar; 48(4):1528-34. PMID: 17389481
Purpose: To evaluate the efficacy and safety of a novel sutureless transplantation of bioadhesive-coated, sterilized, freeze-dried amniotic membrane (FD-AM) for ocular surface reconstruction. Methods: A bioadhesive-coated, freeze-dried amniotic membrane was...
8.
Nakamura T, Inatomi T, Cooper L, Rigby H, Fullwood N, Kinoshita S
Ophthalmology . 2007 Feb; 114(6):1080-8. PMID: 17275911
Purpose: To determine the epithelial lineage of origin of surgically removed grafts after autologous cultivated oral mucosal epithelial transplantation (COMET). Design: Retrospective comparative case series. Participants: We studied 6 eyes...
9.
Walsh M, Singh M, Pollock H, Cooper L, German M, Stringfellow H, et al.
Biochem Biophys Res Commun . 2006 Dec; 352(1):213-9. PMID: 17141660
Although cervical cancer screening in the UK has led to reductions in the incidence of invasive disease, this programme remains flawed. We set out to examine the potential of infrared...
10.
Cooper L, Bentley A, Nieduszynski I, Talabani S, Thomson A, Utani A, et al.
Invest Ophthalmol Vis Sci . 2006 Aug; 47(8):3303-10. PMID: 16877395
Purpose: Dermatopontin (DPT) is an abundant component of the stromal extracellular matrix; however, its function in the cornea is poorly understood. This study was conducted to determine whether DPT has...