Leandro Jimenez
Overview
Explore the profile of Leandro Jimenez including associated specialties, affiliations and a list of published articles.
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10
Citations
484
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Recent Articles
1.
Jimenez L, Campos Codo A, Sampaio V, Oliveira A, Ferreira L, Davanzo G, et al.
Front Med (Lausanne)
. 2021 Sep;
8:637885.
PMID: 34490283
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect a broad range of human tissues by using the host receptor angiotensin-converting enzyme 2 (ACE2). Individuals with comorbidities associated with...
2.
Xu T, Schutte A, Jimenez L, Goncalves A, Keller A, Pipkin M, et al.
J Immunol
. 2021 Apr;
206(9):2170-2183.
PMID: 33863789
The transcriptional and epigenetic regulation of CD8 T cell differentiation is critical for balancing pathogen eradication and long-term immunity by effector and memory CTLs, respectively. In this study, we demonstrate...
3.
de Conti A, Tryndyak V, Heidor R, Jimenez L, Moreno F, Beland F, et al.
J Nutr Biochem
. 2020 Sep;
86:108496.
PMID: 32920087
Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers. The rising incidence of HCC worldwide and its resistance to pharmacotherapy indicate that the prevention of HCC development may...
4.
Pinto B, Oliveira A, Singh Y, Jimenez L, Goncalves A, Ogava R, et al.
J Infect Dis
. 2020 Jun;
222(4):556-563.
PMID: 32526012
Patients who died from COVID-19 often had comorbidities, such as hypertension, diabetes, and chronic obstructive lung disease. Although angiotensin-converting enzyme 2 (ACE2) is crucial for SARS-CoV-2 to bind and enter...
5.
Pinto B, Oliveira A, Singh Y, Jimenez L, Goncalves A, Ogava R, et al.
medRxiv
. 2020 Jun;
PMID: 32511627
The pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in several thousand deaths worldwide in just a few months. Patients who died from Coronavirus disease...
6.
Jimenez L, Perez R, Sao Juliao G, Vailati B, Fernandez L, Gama-Rodrigues J, et al.
Dis Colon Rectum
. 2019 Dec;
63(3):300-309.
PMID: 31842156
Background: Patients with rectal cancer may undergo neoadjuvant chemoradiation even in early stages in an attempt to achieve complete clinical response and undergo organ preservation. However, prediction of tumor response...
7.
Chopra S, Giovanelli P, Alvarado-Vazquez P, Alonso S, Song M, Sandoval T, et al.
Science
. 2019 Jul;
365(6450).
PMID: 31320508
Inositol-requiring enzyme 1[α] (IRE1[α])-X-box binding protein spliced (XBP1) signaling maintains endoplasmic reticulum (ER) homeostasis while controlling immunometabolic processes. Yet, the physiological consequences of IRE1α-XBP1 activation in leukocytes remain unexplored. We...
8.
Borowa-Mazgaj B, de Conti A, Tryndyak V, Steward C, Jimenez L, Melnyk S, et al.
Toxicol Sci
. 2019 May;
170(2):273-282.
PMID: 31086990
Nonalcoholic fatty liver disease (NAFLD) is becoming a major etiological risk factor for hepatocellular carcinoma (HCC) in the United States and other Western countries. In this study, we investigated the...
9.
Pogribny I, Dreval K, Kindrat I, Melnyk S, Jimenez L, de Conti A, et al.
FASEB J
. 2017 Nov;
32(3):1591-1601.
PMID: 29127188
The substantial rise in the prevalence of nonalcoholic steatohepatitis (NASH), an advanced form of nonalcoholic fatty liver disease, and the strong association between NASH and the development of hepatocellular carcinoma...
10.
Campesato L, Barroso-Sousa R, Jimenez L, Correa B, Sabbaga J, Hoff P, et al.
Oncotarget
. 2015 Oct;
6(33):34221-7.
PMID: 26439694
Cancer gene panels (CGPs) are already used in clinical practice to match tumor's genetic profile with available targeted therapies. We aimed to determine if CGPs could also be applied to...