Leandro Ceotto Freitas-Lima
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Explore the profile of Leandro Ceotto Freitas-Lima including associated specialties, affiliations and a list of published articles.
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14
Citations
87
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Recent Articles
1.
Freitas-Lima L, Pacesova A, Stanurova J, Sacha P, Marek A, Hubalek M, et al.
Eur J Pharmacol
. 2023 Apr;
949:175713.
PMID: 37054941
Cocaine- and amphetamine-regulated transcript peptide (CARTp) is an anorexigenic neuropeptide whose receptor is undisclosed. Previously, we reported the specific binding of CART(61-102) to pheochromocytoma PC12 cells, where CART(61-102) affinity and...
2.
Arruda A, Budu A, de Menezes T, Bader M, Carvalho Araujo R, Freitas-Lima L
Life Sci
. 2022 Oct;
309:121034.
PMID: 36208659
Aims: To investigate how the kinin B1 receptor (B1R) modulates mitochondrial activity under stress conditions, focusing on the rate of energy expenditure and shift in metabolism. Main Methods: Wild-type and...
3.
Freitas-Lima L, Budu A, Estrela G, Alves-Silva T, Perilhao M, Arruda A, et al.
Life Sci
. 2021 Oct;
294:120007.
PMID: 34600938
Aims: To analyze the hepatic metabolism in kinin B1 receptor deficient mice (B1KO mice) under fasting conditions. Main Methods: WT and B1KO male mice were allocated in a calorimetric cage...
4.
Delgado N, Rouver W, Freitas-Lima L, Vieira-Alves I, Lemos V, Santos R
Front Physiol
. 2021 Aug;
12:659291.
PMID: 34393807
Background: The protective effect of estrogen on the vasculature cannot be explained only by its action through the receptors ERα and ERβ. G protein-coupled estrogen receptors (GPER)-which are widely distributed...
5.
Estrela G, Freitas-Lima L, Budu A, de Arruda A, Perilhao M, Fock R, et al.
Biomedicines
. 2021 Aug;
9(7).
PMID: 34356833
Anemia is a common feature of chronic kidney disease (CKD). It is a process related to erythropoietin deficiency, shortened erythrocyte survival, uremic erythropoiesis inhibitors, and disordered iron homeostasis. Animal models...
6.
Stela Medeiros C, de Sousa Neto I, Silva K, Cantuaria A, Rezende T, Franco O, et al.
Nutrients
. 2021 Jul;
13(6).
PMID: 34201185
High-protein diets (HPDs) are widely accepted as a way to stimulate muscle protein synthesis when combined with resistance training (RT). However, the effects of HPDs on adipose tissue plasticity and...
7.
Freitas-Lima L, Budu A, Arruda A, Perilhao M, Barrera-Chimal J, Carvalho Araujo R, et al.
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33049997
Cisplatin is a chemotherapy drug widely used in the treatment of solid tumors. However, nephrotoxicity has been reported in about one-third of patients undergoing cisplatin therapy. Proximal tubules are the...
8.
Hungaro T, Freitas-Lima L, Gregnani M, Perilhao M, Alves-Silva T, Arruda A, et al.
Front Physiol
. 2020 Aug;
11:768.
PMID: 32765291
Lipopolysaccharide (LPS) is a systemic response-triggering endotoxin, which has the kidney as one of its first targets, thus causing acute injuries to this organ. Physical exercise is capable of promoting...
9.
Estrela G, Arruda A, Torquato H, Freitas-Lima L, Perilhao M, Wasinski F, et al.
Int J Mol Sci
. 2020 Jul;
21(14).
PMID: 32708962
Hypercholesterolemia, also called high cholesterol, is a form of hyperlipidemia, which may be a consequence of diet, obesity or diabetes. In addition, increased levels of low-density lipoprotein (LDL) and reduced...
10.
Cavalcante P, Alenina N, Budu A, Freitas-Lima L, Alves-Silva T, Henao Agudelo J, et al.
Mediators Inflamm
. 2019 Jul;
2019:9086758.
PMID: 31360120
Macrophages contribute to a continuous increase in blood pressure and kidney damage in hypertension, but their polarization status and the underlying mechanisms have not been clarified. This study revealed an...