Leah Alcock
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Explore the profile of Leah Alcock including associated specialties, affiliations and a list of published articles.
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6
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223
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Recent Articles
1.
Piskareva O, Harvey H, Nolan J, Conlon R, Alcock L, Buckley P, et al.
Cancer Lett
. 2015 May;
364(2):142-55.
PMID: 25960282
Neuroblastoma is a challenging childhood malignancy, with a very high percentage of patients relapsing following acquisition of drug resistance, thereby necessitating the identification of mechanisms of drug resistance as well...
2.
Buckley P, Alcock L, Heffernan J, Woods J, Brett F, Stallings R, et al.
J Neuropathol Exp Neurol
. 2011 Feb;
70(3):177-82.
PMID: 21293300
Loss of chromosome 1p/19q in oligodendrogliomas represents a powerful predictor of good prognosis. Expression of internexin (INA), a neuronal specific intermediate filament protein, has recently been proposed as a surrogate...
3.
Buckley P, Das S, Bryan K, Watters K, Alcock L, Koster J, et al.
Int J Cancer
. 2010 Jul;
128(10):2296-305.
PMID: 20669225
The downregulation of specific genes through DNA hypermethylation is a major hallmark of cancer, although the extent and genomic distribution of hypermethylation occurring within cancer genomes is poorly understood. We...
4.
Buckley P, Alcock L, Bryan K, Bray I, Schulte J, Schramm A, et al.
Clin Cancer Res
. 2010 Apr;
16(11):2971-8.
PMID: 20406844
Purpose: The purpose of this study was to further define the biology of the 11q- neuroblastoma tumor subgroup by the integration of array-based comparative genomic hybridization with microRNA (miRNA) expression...
5.
Murphy D, Buckley P, Bryan K, Das S, Alcock L, Foley N, et al.
PLoS One
. 2009 Dec;
4(12):e8154.
PMID: 19997598
Background: Neuroblastoma, a cancer derived from precursor cells of the sympathetic nervous system, is a major cause of childhood cancer related deaths. The single most important prognostic indicator of poor...
6.
Bray I, Bryan K, Prenter S, Buckley P, Foley N, Murphy D, et al.
PLoS One
. 2009 Nov;
4(11):e7850.
PMID: 19924232
MiRNAs regulate gene expression at a post-transcriptional level and their dysregulation can play major roles in the pathogenesis of many different forms of cancer, including neuroblastoma, an often fatal paediatric...