Lawrence Sher
Overview
Explore the profile of Lawrence Sher including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
2165
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0
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Recent Articles
11.
Deleuran M, Thaci D, Beck L, de Bruin-Weller M, Blauvelt A, Forman S, et al.
J Am Acad Dermatol
. 2019 Aug;
82(2):377-388.
PMID: 31374300
Background: Significant unmet need exists for long-term treatment of moderate to severe atopic dermatitis (AD). Objective: To assess the long-term safety and efficacy of dupilumab in patients with AD. Methods:...
12.
Maspero J, Katelaris C, Busse W, Castro M, Corren J, Chipps B, et al.
J Allergy Clin Immunol Pract
. 2019 Jul;
8(2):527-539.e9.
PMID: 31351189
Background: Dupilumab, a fully human monoclonal antibody, blocks the shared receptor component for IL-4 and IL-13 signaling, key drivers of type 2 inflammation. In the phase 3 study (NCT02414854), add-on...
13.
Vickery B, Vereda A, Casale T, Beyer K, Du Toit G, Hourihane J, et al.
N Engl J Med
. 2018 Nov;
379(21):1991-2001.
PMID: 30449234
Background: Peanut allergy, for which there are no approved treatment options, affects patients who are at risk for unpredictable and occasionally life-threatening allergic reactions. Methods: In a phase 3 trial,...
14.
Kerwin E, Wachtel A, Sher L, Nyberg J, Darken P, Siddiqui S, et al.
Respir Med
. 2018 Jun;
139:39-47.
PMID: 29858000
Objectives: This randomized, double-blind, placebo-controlled, cross-over, Phase II dose-ranging study investigated the efficacy and safety of GP MDI (glycopyrronium administered by metered dose inhaler formulated using co-suspension delivery technology) compared...
15.
Rabe K, Nair P, Brusselle G, Maspero J, Castro M, Sher L, et al.
N Engl J Med
. 2018 May;
378(26):2475-2485.
PMID: 29782224
Background: Dupilumab is a fully human anti-interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13 signaling. Its effectiveness in reducing oral glucocorticoid use in patients with severe asthma...
16.
Castro M, Corren J, Pavord I, Maspero J, Wenzel S, Rabe K, et al.
N Engl J Med
. 2018 May;
378(26):2486-2496.
PMID: 29782217
Background: Dupilumab is a fully human anti-interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma. Methods:...
17.
Calabria C, Hauswirth D, Rank M, Sher L, Larenas-Linnemann D
Allergy Asthma Proc
. 2017 Feb;
38(2):121-129.
PMID: 28234049
Background: Few data exist regarding the use of venom immunotherapy (VIT) in specific high-risk chronic medical conditions and pregnancy, and in young children. Methods: A Web-based survey was sent to...
18.
Wenzel S, Ford L, Pearlman D, Spector S, Sher L, Skobieranda F, et al.
N Engl J Med
. 2013 May;
368(26):2455-66.
PMID: 23688323
Background: Moderate-to-severe asthma remains poorly treated. We evaluated the efficacy and safety of dupilumab (SAR231893/REGN668), a fully human monoclonal antibody to the alpha subunit of the interleukin-4 receptor, in patients...
19.
Rubino C, Ambrose P, Cirincione B, Arguedas A, Sher L, Lopez E, et al.
Diagn Microbiol Infect Dis
. 2007 Sep;
59(1):67-74.
PMID: 17875453
Gatifloxacin is a 4th-generation fluoroquinolone previously under investigation for the treatment of otitis media in infants and children. These analyses were designed to evaluate the extent of drug exposure relative...
20.
Sher L, Arguedas A, Husseman M, Pichichero M, Hamed K, Biswas D, et al.
Pediatr Infect Dis J
. 2005 Apr;
24(4):301-8.
PMID: 15818288
Background: Recurrent otitis media and acute otitis media treatment failure are commonly encountered in the pediatric population. Objective: To compare the clinical efficacy of gatifloxacin with amoxicillin/clavulanate for the treatment...