Lawrence J Coppey
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Explore the profile of Lawrence J Coppey including associated specialties, affiliations and a list of published articles.
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40
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1313
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Recent Articles
11.
Yorek M, Coppey L, Shevalye H, Obrosov A, Kardon R, Yorek M
J Nutr Metab
. 2016 Oct;
2016:5905891.
PMID: 27774316
. In this study a streptozotocin induced type 1 diabetes mouse model was used to assess the effectiveness of salsalate, menhaden oil, the combination of salsalate and menhaden oil, or...
12.
Trammell S, Weidemann B, Chadda A, Yorek M, Holmes A, Coppey L, et al.
Sci Rep
. 2016 May;
6:26933.
PMID: 27230286
Male C57BL/6J mice raised on high fat diet (HFD) become prediabetic and develop insulin resistance and sensory neuropathy. The same mice given low doses of streptozotocin are a model of...
13.
Yorek M, Davidson E, Poolman P, Coppey L, Obrosov A, Holmes A, et al.
Invest Ophthalmol Vis Sci
. 2016 May;
57(6):2412-9.
PMID: 27145474
Purpose: Diagnosis of peripheral neuropathy (PN), which affects approximately 50% of the diabetic population, is subjective, with many patients seeking a diagnosis only after presenting with symptoms. Recently, in vivo...
14.
Davidson E, Holmes A, Coppey L, Yorek M
Eur J Pharmacol
. 2015 Aug;
765:258-67.
PMID: 26291662
We have previously demonstrated that treating diabetic rats with enalapril, an angiotensin converting enzyme (ACE) inhibitor, α-lipoic acid, an antioxidant, or menhaden oil, a natural source of omega-3 fatty acids...
15.
Holmes A, Coppey L, Davidson E, Yorek M
J Diabetes Res
. 2015 Aug;
2015:307285.
PMID: 26229968
We examined whether reversal of high fat diet, stimulating weight loss, compared to two treatments previously shown to have beneficial effects, could improve glucose utilization and peripheral neuropathy in animal...
16.
Shevalye H, Yorek M, Coppey L, Holmes A, Harper M, Kardon R, et al.
J Neurophysiol
. 2015 May;
114(1):199-208.
PMID: 25925322
The purpose of this study was to determine the effect of supplementing the diet of a mouse model of type 2 diabetes with menhaden (fish) oil or daily treatment with...
17.
Coppey L, Davidson E, Obrosov A, Yorek M
J Neurophysiol
. 2014 Nov;
113(3):701-8.
PMID: 25376787
The purpose of this study was to determine the effect of supplementing the diet of type 1 diabetic rats with menhaden oil on diabetic neuropathy. Menhaden oil is a natural...
18.
Davidson E, Coppey L, Holmes A, Lupachyk S, Dake B, Oltman C, et al.
J Diabetes Res
. 2014 Nov;
2014:714273.
PMID: 25371906
Recently a new rat model for type 2 diabetes the Zucker diabetic Sprague-Dawley (ZDSD/Pco) was created. In this study we sought to characterize the development of diabetic neuropathy in ZDSD...
19.
Davidson E, Coppey L, Kardon R, Yorek M
Invest Ophthalmol Vis Sci
. 2014 Feb;
55(3):1222-30.
PMID: 24519423
Purpose: Peripheral neuropathy has been shown to exist in prediabetic and diabetic patients and animal models. However, the development of peripheral neuropathy in prediabetes and posthyperglycemia is likely different. The...
20.
Davidson E, Coppey L, Yorek M
Invest Ophthalmol Vis Sci
. 2012 Nov;
53(13):8067-74.
PMID: 23169880
Purpose: Cornea confocal microscopy is emerging as a clinical tool to evaluate the development and progression of diabetic neuropathy. The purpose of these studies was to characterize the early changes...