Lawrence C Shimmin
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Explore the profile of Lawrence C Shimmin including associated specialties, affiliations and a list of published articles.
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34
Citations
478
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Recent Articles
1.
Gu X, Gu D, He J, Rao D, Hixson J, Chen J, et al.
Am J Hypertens
. 2017 Oct;
31(2):205-211.
PMID: 29036630
Background: A resequencing study of renal epithelial sodium channel (ENaC) genes was conducted to identify rare variants associated with blood pressure (BP) salt-sensitivity. Methods: The Genetic Epidemiology Network of Salt-Sensitivity...
2.
Hixson J, Jun G, Shimmin L, Wang Y, Yu G, Mao C, et al.
Sci Rep
. 2017 Jun;
7(1):4091.
PMID: 28642624
We investigated the influence of genetic variants on atherosclerosis using whole exome sequencing in cases and controls from the autopsy study "Pathobiological Determinants of Atherosclerosis in Youth (PDAY)". We identified...
3.
Ray E, Chen J, Kelly T, He J, Hamm L, Gu D, et al.
Am J Physiol Renal Physiol
. 2016 Sep;
311(5):F908-F914.
PMID: 27582106
Mutations in genes encoding subunits of the epithelial Na channel (ENaC) can cause early onset familial hypertension, demonstrating the importance of this channel in modulating blood pressure. It remains unclear...
4.
He W, Li C, Rao D, Hixson J, Huang J, Cao J, et al.
Am J Hypertens
. 2015 Mar;
28(11):1310-5.
PMID: 25820244
Background: The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure (BP) regulation. The current study uses single-marker and gene-based analyses to examine the association between RAAS genes and...
5.
Li C, Bazzano L, Rao D, Hixson J, He J, Gu D, et al.
J Genet Genomics
. 2015 Mar;
42(3):107-17.
PMID: 25819087
We conducted a genome-wide linkage scan and positional association study to identify genes and variants influencing blood lipid levels among participants of the Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study....
6.
Liu F, He J, Gu D, Rao D, Huang J, Hixson J, et al.
Am J Hypertens
. 2014 Nov;
28(6):780-8.
PMID: 25424718
Background: We used single-marker and novel gene-based methods to examine the associations of endothelial system genes with blood pressure (BP) changes and hypertension in a longitudinal family study. Methods: The...
7.
Yang X, Gu D, He J, Hixson J, Rao D, Lu F, et al.
Circ Cardiovasc Genet
. 2014 Jul;
7(4):521-8.
PMID: 25028485
Background: Blood pressure (BP) response to cold pressor test (CPT) is associated with increased risk of cardiovascular disease. We performed a genome-wide linkage scan and regional association analysis to identify...
8.
Li C, Yang X, He J, Hixson J, Gu D, Rao D, et al.
PLoS One
. 2014 Jun;
9(5):e98432.
PMID: 24878720
Background: Serum and glucocorticoid regulated kinase (SGK) plays a critical role in the regulation of renal sodium transport. We examined the association between SGK genes and salt sensitivity of blood...
9.
Howard T, Mathias R, Seeds M, Herrington D, Hixson J, Shimmin L, et al.
PLoS One
. 2014 May;
9(5):e97510.
PMID: 24842322
Levels of omega-6 (n-6) and omega-3 (n-3), long chain polyunsaturated fatty acids (LcPUFAs) such as arachidonic acid (AA; 20:4, n-6), eicosapentaenoic acid (EPA; 20:5, n-3) and docosahexaenoic acid (DHA; 22:6,...
10.
Yang X, He J, Gu D, Hixson J, Huang J, Rao D, et al.
Am J Hypertens
. 2014 Apr;
27(11):1370-6.
PMID: 24735600
Background: We examined the associations of epithelial sodium channel (ENaC) genes with blood pressure (BP) changes and hypertension incidence in a longitudinal family study. Methods: A total of 2,755 Han...