Lawrence B Blyn
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Explore the profile of Lawrence B Blyn including associated specialties, affiliations and a list of published articles.
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43
Citations
1436
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Recent Articles
1.
Jia B, Lovari R, Miller H, Metzgar D, Massire C, Carolan H, et al.
Diagn Microbiol Infect Dis
. 2020 Feb;
97(1):114988.
PMID: 32107092
The incidence of invasive fungal infections is on the rise worldwide due to the growth of the immunocompromised population. We report here the use of a diagnostic assay that utilizes...
2.
Hong G, White M, Lechtzin N, West N, Avery R, Miller H, et al.
J Cyst Fibros
. 2017 Feb;
16(2):e3-e7.
PMID: 28185887
Background: Disseminated fungal infections are a known serious complication in individuals with cystic fibrosis (CF) following orthotopic lung transplantation. Aspergillus fumigatus and Scedosporium species are among the more common causes...
3.
Metzgar D, Frinder M, Rothman R, Peterson S, Carroll K, Zhang S, et al.
PLoS One
. 2016 Jul;
11(7):e0158186.
PMID: 27384540
Unlabelled: Bloodstream infection (BSI) and sepsis are rising in incidence throughout the developed world. The spread of multi-drug resistant organisms presents increasing challenges to treatment. Surviving BSI is dependent on...
4.
Bacconi A, Richmond G, Baroldi M, Laffler T, Blyn L, Carolan H, et al.
J Clin Microbiol
. 2014 Jun;
52(9):3164-74.
PMID: 24951806
The rapid identification of bacteria and fungi directly from the blood of patients with suspected bloodstream infections aids in diagnosis and guides treatment decisions. The development of an automated, rapid,...
5.
Metzgar D, Lovari R, Ray K, Baynes D, Drapp D, Frinder M, et al.
J Clin Virol
. 2014 Jan;
59(3):177-83.
PMID: 24440177
Background: Diverse viruses often reactivate in or infect cancer patients, patients with immunocompromising infections or genetic conditions, and transplant recipients undergoing immunosuppressive therapy. These infections can disseminate, leading to death,...
6.
Kecojevic A, Ranken R, Ecker D, Massire C, Sampath R, Blyn L, et al.
BMC Infect Dis
. 2014 Jan;
14:16.
PMID: 24405766
Background: A limitation of both culture-based and molecular methods of screening for staphylococcal infection is that current tests determine only the presence or absence of colonization with no information on...
7.
Laffler T, Cummins L, McClain C, Quinn C, Toro M, Carolan H, et al.
J Clin Microbiol
. 2013 Aug;
51(11):3535-41.
PMID: 23966503
A prospective study was performed to determine the value of direct molecular testing of whole blood for detecting the presence of culturable and unculturable bacteria and yeasts in patients with...
8.
Metzgar D, Frinder M, Lovari R, Toleno D, Massire C, Blyn L, et al.
J Clin Microbiol
. 2013 Jun;
51(8):2670-8.
PMID: 23761152
We describe an assay which uses broad-spectrum, conserved-site PCR paired with mass spectrometry analysis of amplicons (PCR/electrospray ionization-mass spectrometry [ESI-MS]) to detect and identify diverse bacterial and Candida species in...
9.
Jordana-Lluch E, Carolan H, Gimenez M, Sampath R, Ecker D, Quesada M, et al.
PLoS One
. 2013 Apr;
8(4):e62108.
PMID: 23626775
Achieving a rapid microbiological diagnosis is crucial for decreasing morbidity and mortality of patients with a bloodstream infection, as it leads to the administration of an appropriate empiric antimicrobial therapy....
10.
Massire C, Buelow D, Zhang S, Lovari R, Matthews H, Toleno D, et al.
J Clin Microbiol
. 2013 Jan;
51(3):959-66.
PMID: 23303501
Invasive fungal infections are a significant cause of morbidity and mortality among immunocompromised patients. Early and accurate identification of these pathogens is central to direct therapy and to improve overall...