Lawrence A David
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Explore the profile of Lawrence A David including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Capra B, Hudson S, Helder M, Laskaridou E, Johnson A, Gilmore C, et al.
Contemp Clin Trials
. 2024 Jan;
137:107427.
PMID: 38184104
Background: Aging is associated with gut dysbiosis, low-grade inflammation, and increased risk of type 2 diabetes (T2D). Prediabetes, which increases T2D and cardiovascular disease risk, is present in 45-50% of...
12.
Letourneau J, Walker L, Han S, David L, Younge N
bioRxiv
. 2023 Aug;
PMID: 37645803
The infant gut microbiome is a crucial factor in health and development. In preterm infants, altered gut microbiome composition and function have been linked to serious neonatal complications such as...
13.
Petrone B, Aqeel A, Jiang S, Durand H, Dallow E, McCann J, et al.
Proc Natl Acad Sci U S A
. 2023 Jun;
120(27):e2304441120.
PMID: 37368926
Eating a varied diet is a central tenet of good nutrition. Here, we develop a molecular tool to quantify human dietary plant diversity by applying DNA metabarcoding with the chloroplast...
14.
Davey L, Malkus P, Villa M, Dolat L, Holmes Z, Letourneau J, et al.
Nat Microbiol
. 2023 Jun;
8(8):1450-1467.
PMID: 37337046
Akkermansia muciniphila, a mucophilic member of the gut microbiota, protects its host against metabolic disorders. Because it is genetically intractable, the mechanisms underlying mucin metabolism, gut colonization and its impact...
15.
Midani F, David L
Front Microbiol
. 2023 Jan;
13:910390.
PMID: 36687598
Cross feeding between microbes is ubiquitous, but its impact on the diversity and productivity of microbial communities is incompletely understood. A reductionist approach using simple microbial communities has the potential...
16.
Wang T, Weiss A, Aqeel A, Wu F, Lopatkin A, David L, et al.
Nat Chem Biol
. 2022 Sep;
18(11):1245-1252.
PMID: 36050493
The functions of many microbial communities exhibit remarkable stability despite fluctuations in the compositions of these communities. To date, a mechanistic understanding of this function-composition decoupling is lacking. Statistical mechanisms...
17.
Holmes Z, Tang H, Liu C, Bush A, Neubert B, Jiao Y, et al.
Blood
. 2022 Aug;
140(21):2300-2304.
PMID: 35930748
No abstract available.
18.
Holmes Z, Villa M, Durand H, Jiang S, Dallow E, Petrone B, et al.
Microbiome
. 2022 Jul;
10(1):114.
PMID: 35902900
Background: Short-chain fatty acids (SCFAs) derived from gut bacteria are associated with protective roles in diseases ranging from obesity to colorectal cancers. Intake of microbially accessible dietary fibers (prebiotics) lead...
19.
Letourneau J, Holmes Z, Dallow E, Durand H, Jiang S, Carrion V, et al.
ISME J
. 2022 Jul;
16(11):2479-2490.
PMID: 35871250
Many ecosystems have been shown to retain a memory of past conditions, which in turn affects how they respond to future stimuli. In microbial ecosystems, community disturbance has been associated...
20.
Wu F, Ha Y, Weiss A, Wang M, Letourneau J, Wang S, et al.
Nat Chem Biol
. 2022 Feb;
18(4):394-402.
PMID: 35145274
Microbial communities inhabit spatial architectures that divide a global environment into isolated or semi-isolated local environments, which leads to the partitioning of a microbial community into a collection of local...