Laurephile Desrosiers
Overview
Explore the profile of Laurephile Desrosiers including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
80
Followers
0
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Recent Articles
1.
Clark-Patterson G, Roy S, Desrosiers L, Knoepp L, Sen A, Miller K
Sci Rep
. 2021 Oct;
11(1):20956.
PMID: 34697337
The vagina plays a critical role in supporting the pelvic organs and loss of support leads to pelvic organ prolapse. It is unknown what microstructural changes influence prolapse progression nor...
2.
Clark-Patterson G, McGuire J, Desrosiers L, Knoepp L, De Vita R, Miller K
J Biomech Eng
. 2021 Sep;
143(12).
PMID: 34494082
The vagina is a viscoelastic fibromuscular organ that provides support to the pelvic organs. The viscoelastic properties of the vagina are understudied but may be critical for pelvic stability. Most...
3.
Conway C, White S, Russell R, Sentilles C, Clark-Patterson G, Miller K, et al.
Ochsner J
. 2021 Jan;
20(4):410-418.
PMID: 33408579
Pelvic organ prolapse (POP) affects a significant portion of the female population, impacting quality of life and often requiring intervention. The exact cause of prolapse is unknown. We review some...
4.
Desrosiers L, Knoepp L
Ochsner J
. 2021 Jan;
20(4):400-409.
PMID: 33408578
Botulinum toxin is an injectable neuromodulator that inhibits transmission between peripheral nerve endings and muscle fibers, resulting in muscle paralysis. Botulinum toxin type A is the most common form of...
5.
Danso E, Schuster J, Johnson I, Harville E, Buckner L, Desrosiers L, et al.
Sci Rep
. 2020 May;
10(1):7386.
PMID: 32355180
Uterosacral ligaments (USLs) provide structural support to the female pelvic floor, and a loss of USL structural integrity or biomechanical function may induce pelvic organ prolapse (POP). Alterations in extracellular...
6.
Conway C, Qureshi H, Morris V, Danso E, Desrosiers L, Knoepp L, et al.
J Biomech
. 2019 Jul;
94:39-48.
PMID: 31353018
From a biomechanical perspective, female reproductive health is an understudied area of research. There is an incomplete understanding of the complex function and interaction between the cervix and uterus. This,...
7.
Clark G, Pokutta-Paskaleva A, Lawrence D, Lindsey S, Desrosiers L, Knoepp L, et al.
Interface Focus
. 2019 Jul;
9(4):20190025.
PMID: 31263538
Pelvic organ prolapse is characterized as the descent of the pelvic organs into the vaginal canal. In the USA, there is a 12% lifetime risk for requiring surgical intervention. Although...
8.
Capone D, Clark G, Bivona D, Ogola B, Desrosiers L, Knoepp L, et al.
J Biomech
. 2018 Nov;
82:299-306.
PMID: 30458959
Mounting evidence suggests that cells within soft tissues seek to maintain a preferred biomechanical state. Residual stress is defined as the stress that remains in a tissue when all external...
9.
Akintunde A, Robison K, Capone D, Desrosiers L, Knoepp L, Miller K
J Biomech Eng
. 2018 Nov;
141(2).
PMID: 30453317
Although the underlying mechanisms of pelvic organ prolapse (POP) remain unknown, disruption of elastic fiber metabolism within the vaginal wall extracellular matrix (ECM) has been highly implicated. It has been...
10.
Robison K, Conway C, Desrosiers L, Knoepp L, Miller K
J Biomech Eng
. 2017 Aug;
139(10).
PMID: 28787477
Progress toward understanding the underlying mechanisms of pelvic organ prolapse (POP) is limited, in part, due to a lack of information on the biomechanical properties and microstructural composition of the...