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Laurent Preynat

Explore the profile of Laurent Preynat including associated specialties, affiliations and a list of published articles. Areas
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Villetti G, Carnini C, Battipaglia L, Preynat L, Bolzoni P, Bassani F, et al.
J Pharmacol Exp Ther . 2015 Jan; 352(3):568-78. PMID: 25576073
CHF6001 [(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(3-(cyclopropylmethoxy)-4-(methylsulfonamido)benzoyloxy)ethyl)pyridine 1-oxide] is a novel phosphodiesterase 4 (PDE4) inhibitor designed for use in pulmonary diseases by inhaled administration. Intratracheal administration of CHF6001 to ovalbumin-sensitized Brown-Norway rats suppressed the antigen-induced...