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Laurent Dubuquoy

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Articles 91
Citations 2562
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Recent Articles
1.
Gellee N, Legrand N, Jouve M, Devaux P, Dubuquoy L, Sobolewski C
Cancers (Basel) . 2025 Feb; 17(3). PMID: 39941720
Chronic liver diseases, such as those encountered with obesity, chronic/abusive alcohol consumption or viral infections, represent not only major public health concerns with limited therapeutic options but also important risk...
2.
Ponzoni A, Speca S, Hartle M, Gerstenberg A, Tomezyk A, Senechal V, et al.
Metabolomics . 2024 Dec; 21(1):5. PMID: 39674857
Introduction: Inflammatory bowel diseases (IBDs) are chronic immune driven intestinal disorders with marked metabolic alteration. Mass spectrometry imaging (MSI) enables the direct visualization of biomolecules within tissues and facilitates the...
3.
Barczyk A, Six P, Rivoal M, Devos C, Dezitter X, Cornu-Choi M, et al.
J Med Chem . 2024 Oct; 67(21):19304-19322. PMID: 39444201
Inflammation is a defense mechanism that restores tissue damage and eliminates pathogens. Among the pattern recognition receptors that recognize danger or pathogenic signals, nucleotide oligomerization domains 1 and 2 (NOD1/2)...
4.
Djouina M, Ollivier A, Waxin C, Kervoaze G, Pichavant M, Caboche S, et al.
J Xenobiot . 2024 Jul; 14(3):950-969. PMID: 39051349
Although the effects of cigarette smoke (CS) on the development of several intestinal diseases is well documented, the impact of e-cigarette aerosol (e-cig) on digestive health is largely unknown. To...
5.
Very N, Boulet C, Gheeraert C, Berthier A, Johanns M, Bou Saleh M, et al.
Cell Death Dis . 2024 Jun; 15(6):391. PMID: 38830870
Tissue injury causes activation of mesenchymal lineage cells into wound-repairing myofibroblasts (MFs), whose uncontrolled activity ultimately leads to fibrosis. Although this process is triggered by deep metabolic and transcriptional reprogramming,...
6.
Rivoal M, Dubuquoy L, Millet R, Leleu-Chavain N
J Med Chem . 2023 Oct; 66(21):14391-14410. PMID: 37857324
Receptor interacting serine/threonine protein kinase 2 (RIPK2) is a downstream signaling molecule essential for the activation of several innate immune receptors, including the NOD-like receptors (NOD1 and NOD2). Recognition of...
7.
Djouina M, Waxin C, Dubuquoy L, Launay D, Vignal C, Body-Malapel M
Ecotoxicol Environ Saf . 2023 Aug; 264:115417. PMID: 37651791
Accumulating evidence shows widespread contamination of water sources and food with microplastics. Although the liver is one of the main sites of bioaccumulation within the human body, it is still...
8.
Djouina M, Waxin C, Caboche S, Lecointe K, Steimle A, Beury D, et al.
Sci Total Environ . 2023 Jul; 900:165722. PMID: 37482350
Background: The mycotoxin deoxynivalenol (DON) is a frequent contaminant of grain and cereal products worldwide. Exposure to DON can cause gastrointestinal inflammation, disturb gut barrier function, and induce gut dysbiosis...
9.
Dubois-Chevalier J, Gheeraert C, Berthier A, Boulet C, Dubois V, Guille L, et al.
EMBO Rep . 2023 Jul; 24(9):e57020. PMID: 37424431
Cell identity is specified by a core transcriptional regulatory circuitry (CoRC), typically limited to a small set of interconnected cell-specific transcription factors (TFs). By mining global hepatic TF regulons, we...
10.
Brinkhuizen C, Shapman D, Lebon A, Benard M, Tardivel M, Dubuquoy L, et al.
Biomol Concepts . 2023 Jun; 14(1). PMID: 37377352
Vaccination through the upper respiratory tract is a promising strategy, and particulate antigens, such as antigens associated with nanoparticles, triggered a stronger immune response than the sole antigens. Cationic maltodextrin-based...