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Laurens Vandebroek

Explore the profile of Laurens Vandebroek including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 30
Followers 0
Related Specialty
Chemistry
Top 10 Co-Authors
Tatjana N Parac-Vogt
Luc Van Meervelt
Annelies Sap
Paul Proost
Jeremy R H Tame
Shorok A M Abdelhameed
Arnout R D Voet
Sarah Lentink
Anne des Rieux
Francisco de Azambuja
Published In
Chemistry
Inorg Chem
Faraday Discuss
ACS Omega
Chem Commun (Camb)
Affiliations
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Recent Articles
1.
Fine-tuning non-covalent interactions between hybrid metal-oxo clusters and proteins
Lentink S, Salazar Marcano D, Moussawi M, Vandebroek L, Meervelt L, Parac-Vogt T
Faraday Discuss . 2023 Apr; 244(0):21-38. PMID: 37102318
Interactions between the protein Hen Egg White Lysozyme (HEWL) and three different hybrid Anderson-Evans polyoxometalate clusters - AE-NH2 (δ-[MnMoO{(OCH)CNH}]), AE-CH3 (δ-[MnMoO{(OCH)CCH}]) and AE-Biot (δ-[MnMoO{(OCH)CNHCOCHNOS}]) - were studied tryptophan fluorescence spectroscopy...
2.
Revealing the three-dimensional murine brain microstructure by contrast-enhanced computed tomography
Balcaen T, Piens C, Mwema A, Chourrout M, Vandebroek L, des Rieux A, et al.
Front Neurosci . 2023 Apr; 17:1141615. PMID: 37034159
To improve our understanding of the brain microstructure, high-resolution 3D imaging is used to complement classical 2D histological assessment techniques. X-ray computed tomography allows high-resolution 3D imaging, but requires methods...
3.
Hybrid assemblies of a symmetric designer protein and polyoxometalates with matching symmetry
Vandebroek L, Noguchi H, Kamata K, Tame J, Meervelt L, Parac-Vogt T, et al.
Chem Commun (Camb) . 2020 Sep; 56(78):11601-11604. PMID: 32869783
Novel bioinorganic hybrid materials based on proteins and inorganic clusters have enormous potential for the development of hybrid catalysts that synergistically combine properties of both materials. Here we report the...
4.
Redox Activity of Ce(IV)-Substituted Polyoxometalates toward Amino Acids and Peptides
Abdelhameed S, Vandebroek L, de Azambuja F, Parac-Vogt T
Inorg Chem . 2020 Jun; 59(15):10569-10577. PMID: 32539356
Redox reactions between polyoxometalates (POMs) and biologically relevant molecules have been virtually unexplored but are important, considering the growing interest in the biological applications of POMs. In this work we...
5.
Direct observation of the Zr interaction with the carboxamide bond in a noncovalent complex between Hen Egg White Lysozyme and a Zr-substituted Keggin polyoxometalate
Vandebroek L, Meervelt L, Parac-Vogt T
Acta Crystallogr C Struct Chem . 2018 Nov; 74(Pt 11):1348-1354. PMID: 30398187
The successful cocrystallization of the noncovalent complex formed between (EtNH)[{α-PWOZr-(μ-OH)(HO)}]·7HO Keggin polyoxometalate (2) and Hen Egg White Lysozyme (HEWL) protein is reported. The resulting structural model revealed interaction between monomeric...
6.
Highly Selective and Tunable Protein Hydrolysis by a Polyoxometalate Complex in Surfactant Solutions: A Step toward the Development of Artificial Metalloproteases for Membrane Proteins
Sap A, Vandebroek L, Goovaerts V, Martens E, Proost P, Parac-Vogt T
ACS Omega . 2018 Jul; 2(5):2026-2033. PMID: 30023653
This study represents the first example of protein hydrolysis at pH = 7.4 and 60 °C by a metal-substituted polyoxometalate (POM) in the presence of a zwitterionic surfactant. Edman degradation...
7.
Protein-Assisted Formation and Stabilization of Catalytically Active Polyoxometalate Species
Vandebroek L, De Zitter E, Ly H, Conic D, Mihaylov T, Sap A, et al.
Chemistry . 2018 May; 24(40):10099-10108. PMID: 29797738
The effect of the protein environment on the formation and stabilization of an elusive catalytically active polyoxometalate (POM) species, K [Hf(α -P W O )] (1), is reported. In the...