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Laurence Freedman

Explore the profile of Laurence Freedman including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 3637
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Recent Articles
1.
Kalter-Leibovici O, Murad H, Ziv A, Keidan T, Orion A, Afel Y, et al.
Intern Emerg Med . 2024 Aug; 19(8):2213-2221. PMID: 39154298
Despite progress in therapy, heart failure (HF) inflicts a heavy burden of hospital admissions. In this study, we identified among 1360 community-dwelling HF patients (mean age 70.7 ± 11.3 years,...
2.
Goldberg Y, Amir O, Mandel M, Freedman L, Bar-On Y, Bodenheimer O, et al.
J Clin Epidemiol . 2023 Sep; 163:111-116. PMID: 37774957
Objectives: This study aims to address limitations in assessing vaccine protection using the classical vaccine effectiveness (VE) measure, especially in contexts where a significant portion of the population is already...
3.
Gilboa M, Gonen T, Barda N, Cohn S, Indenbaum V, Weiss-Ottolenghi Y, et al.
JAMA Netw Open . 2023 May; 6(5):e2314757. PMID: 37219906
Importance: A correlation between antibody levels and risk of infection has been demonstrated for the wild-type, Alpha, and Delta SARS-COV-2 variants. High rates of breakthrough infections by the Omicron variant...
4.
Boe L, Shaw P, Midthune D, Gustafson P, Kipnis V, Park E, et al.
Am J Epidemiol . 2023 Apr; 192(8):1406-1414. PMID: 37092245
Regression calibration is a popular approach for correcting biases in estimated regression parameters when exposure variables are measured with error. This approach involves building a calibration equation to estimate the...
5.
Amir O, Goldberg Y, Mandel M, Bar-On Y, Bodenheimer O, Freedman L, et al.
Commun Biol . 2023 Mar; 6(1):315. PMID: 36959496
Following evidence of waning immunity against both infection and severe disease after 2 doses of the BNT162b2 vaccine, Israel began administering a 3rd BNT162b2 dose (booster) in July 2021. Recent...
6.
Amir O, Goldberg Y, Mandel M, Bar-On Y, Bodenheimer O, Freedman L, et al.
Lancet Infect Dis . 2022 Sep; 23(1):67-73. PMID: 36096146
Background: The BNT162b2 (Pfizer-BioNTech) two-dose vaccine regiment for children and the BNT162b2 third dose for adolescents were approved shortly before the SARS-CoV-2 omicron (B.1.1.529) outbreak in Israel. We aimed to...
7.
Lustig Y, Gonen T, Meltzer L, Gilboa M, Indenbaum V, Cohen C, et al.
Nat Immunol . 2022 May; 23(6):940-946. PMID: 35534723
As the effectiveness of a two-dose messenger RNA (mRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine regimen decreases with time, a third dose has been recommended. Here, we assessed...
8.
Bar-On Y, Goldberg Y, Mandel M, Bodenheimer O, Amir O, Freedman L, et al.
N Engl J Med . 2022 Apr; 386(18):1712-1720. PMID: 35381126
Background: On January 2, 2022, Israel began administering a fourth dose of BNT162b2 vaccine to persons 60 years of age or older. Data are needed regarding the effect of the...
9.
Goldberg Y, Mandel M, Woodbridge Y, Fluss R, Novikov I, Yaari R, et al.
Am J Epidemiol . 2022 Mar; 191(8):1420-1428. PMID: 35355048
The worldwide shortage of vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection while the pandemic still remains uncontrolled has led many countries to the dilemma of whether or...
10.
Lustig Y, Zuckerman N, Koren R, Katz-Likvornik S, Yizchaki M, Mendelson E, et al.
Am J Trop Med Hyg . 2022 Feb; 106(4):1121-1125. PMID: 35189591
Zika virus (ZIKV) infection during pregnancy may cause severe fetal abnormalities and therefore it is important to diagnose and distinguish between recent and past Zika infection. Serological diagnosis assays detect...