Laurence C Tisi
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Explore the profile of Laurence C Tisi including associated specialties, affiliations and a list of published articles.
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6
Citations
176
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Recent Articles
1.
Song J, Pandian V, Mauk M, Bau H, Cherry S, Tisi L, et al.
Anal Chem
. 2018 Mar;
90(7):4823-4831.
PMID: 29542319
Rapid and quantitative molecular diagnostics in the field, at home, and at remote clinics is essential for evidence-based disease management, control, and prevention. Conventional molecular diagnostics requires extensive sample preparation,...
2.
McElgunn C, Pereira C, Parham N, Smythe J, Wigglesworth M, Smielewska A, et al.
PLoS One
. 2014 Jan;
9(1):e83808.
PMID: 24416173
Here we describe a method for the detection of Clostridium difficile from stool using a novel low-complexity and rapid extraction process called Heat Elution (HE). The HE method is two-step...
3.
Kiddle G, Hardinge P, Buttigieg N, Gandelman O, Pereira C, McElgunn C, et al.
BMC Biotechnol
. 2012 May;
12:15.
PMID: 22546148
Background: There is an increasing need for quantitative technologies suitable for molecular detection in a variety of settings for applications including food traceability and monitoring of genetically modified (GM) crops...
4.
Gandelman O, Church V, Moore C, Kiddle G, Carne C, Parmar S, et al.
PLoS One
. 2010 Dec;
5(11):e14155.
PMID: 21152399
Background: The real-time monitoring of polynucleotide amplification is at the core of most molecular assays. This conventionally relies on fluorescent detection of the amplicon produced, requiring complex and costly hardware,...
5.
Law G, Gandelman O, Tisi L, Lowe C, Murray J
Biochem J
. 2006 Mar;
397(2):305-12.
PMID: 16551268
Firefly luciferase catalyses a two-step reaction, using ATP-Mg2+, firefly luciferin and molecular oxygen as substrates, leading to the efficient emission of yellow-green light. We report the identification of novel luciferase...
6.
Day J, Tisi L, Bailey M
Luminescence
. 2004 Feb;
19(1):8-20.
PMID: 14981641
Bioluminescence, the conversion of chemical energy into light in living organisms, is dependent on two principal components, an enzyme luciferase and the substrate luciferin. In beetles, the enzyme luciferase has...