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Lauren Kerrigan

Explore the profile of Lauren Kerrigan including associated specialties, affiliations and a list of published articles. Areas
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Citations 44
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Recent Articles
1.
Kerrigan L, Edgar K, Russell-Hallinan A, Cappa O, Glezeva N, Galan-Arriola C, et al.
ESC Heart Fail . 2024 Sep; 12(1):150-165. PMID: 39233619
Aims: Dynamic alterations in cardiac DNA methylation have been implicated in the development of heart failure (HF) with evidence of ischaemic heart disease (IHD); however, there is limited research into...
2.
Russell-Hallinan A, Cappa O, Kerrigan L, Tonry C, Edgar K, Glezeva N, et al.
Cells . 2024 May; 13(9. PMID: 38727290
Dilated cardiomyopathy (DCM) is the most common cause of heart failure, with a complex aetiology involving multiple cell types. We aimed to detect cell-specific transcriptomic alterations in DCM through analysis...
3.
Freimane K, Kerrigan L, Eastwood K, Watson C
Front Bioeng Biotechnol . 2022 Jun; 10:809528. PMID: 35721866
Pre-eclampsia is a serious consideration for women with type 1 diabetes mellitus (T1DM) planning pregnancy. Risk stratification strategies, such as biomarkers measured in the first trimester of pregnancy, could help...
4.
Carlile S, Shiels J, Kerrigan L, Delaney R, Megaw J, Gilmore B, et al.
Sci Rep . 2019 Apr; 9(1):6071. PMID: 30988402
We investigated the anti-inflammatory and antibacterial activities of Hc-cath, a cathelicidin peptide derived from the venom of the sea snake, Hydrophis cyanocyntus, using in vivo models of inflammation and infection....
5.
Small D, Brown R, Doherty D, Abladey A, Zhou-Suckow Z, Delaney R, et al.
Eur Respir J . 2019 Jan; 53(3). PMID: 30655278
Cathepsin S (CatS) is upregulated in the lungs of patients with cystic fibrosis (CF). However, its role in CF lung disease pathogenesis remains unclear.In this study, β-epithelial Na channel-overexpressing transgenic...
6.
Chen Q, Soundara Pandi S, Kerrigan L, McElvaney N, M Greene C, Elborn J, et al.
J Cyst Fibros . 2018 Mar; 17(5):616-623. PMID: 29486923
Background: Previous work suggests that apoptosis is dysfunctional in cystic fibrosis (CF) airways with conflicting results. We evaluated the relationship between dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) and apoptosis...
7.
Bragonzi A, Horati H, Kerrigan L, Lore N, Scholte B, Weldon S
J Cyst Fibros . 2017 Nov; 17(2S):S40-S45. PMID: 29107600
Cystic Fibrosis (CF) lung disease is associated with dysregulation of host defence systems, which ultimately disrupts the balance between inflammation and resolution and leaves the host susceptible to repeated infection....