Lauren E Komer
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Explore the profile of Lauren E Komer including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
88
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0
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Recent Articles
1.
Madangopal R, Zhao Y, Heins C, Zhou J, Liang B, Barbera G, et al.
bioRxiv
. 2025 Mar;
PMID: 40060503
Learning when to initiate or withhold actions is essential for survival and requires integration of past experiences with new information to adapt to changing environments. While stable prelimbic cortex (PL)...
2.
Carnazza K, Komer L, Xie Y, Pineda A, Briano J, Gao V, et al.
Cell Rep
. 2024 May;
43(5):114280.
PMID: 38758645
No abstract available.
3.
Antman-Passig M, Yaari Z, Goerzen D, Parikh R, Chatman S, Komer L, et al.
Nano Lett
. 2023 Oct;
23(23):10687-10695.
PMID: 37889874
Dysregulated lipid metabolism contributes to neurodegenerative pathologies and neurological decline in lysosomal storage disorders as well as more common neurodegenerative diseases. Niemann-Pick type A (NPA) is a fatal neurodegenerative lysosomal...
4.
Madangopal R, Szelenyi E, Nguyen J, Brenner M, Drake O, Pham D, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
119(45):e2209382119.
PMID: 36603188
Studies using rodent models have shown that relapse to drug or food seeking increases progressively during abstinence, a behavioral phenomenon termed "incubation of craving." Mechanistic studies of incubation of craving...
5.
Gao V, Briano J, Komer L, Burre J
J Mol Biol
. 2022 Jul;
435(1):167714.
PMID: 35787839
α-Synuclein is an abundant protein at the neuronal synapse that has been implicated in Parkinson's disease for over 25 years and characterizes the hallmark pathology of a group of neurodegenerative...
6.
Carnazza K, Komer L, Xie Y, Pineda A, Briano J, Gao V, et al.
Cell Rep
. 2022 Apr;
39(2):110675.
PMID: 35417693
α-synuclein, β-synuclein, and γ-synuclein are abundantly expressed proteins in the vertebrate nervous system. α-synuclein functions in neurotransmitter release by binding to and clustering synaptic vesicles and chaperoning SNARE-complex assembly. Pathologically,...
7.
Madangopal R, Ramsey L, Weber S, Brenner M, Lennon V, Drake O, et al.
Neuropsychopharmacology
. 2021 Jun;
46(11):1969-1980.
PMID: 34162997
Persistent susceptibility to cue-induced relapse is a cardinal feature of addiction. Discriminative stimuli (DSs) are one type of drug-associated cue that signal drug availability (DS+) or unavailability (DS-) and control...
8.
Lennon V, Brenner M, Weber S, Komer L, Madangopal R
Bio Protoc
. 2021 Mar;
9(23):e3445.
PMID: 33654940
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency ('') over time. Animal models of incubation may help in developing treatments for relapse prevention. However, these...
9.
Madangopal R, Tunstall B, Komer L, Weber S, Hoots J, Lennon V, et al.
Elife
. 2019 Feb;
8.
PMID: 30801248
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency ('') over time. Animal models of incubation may help develop treatments to prevent relapse, but these models...