Lauren C Tantalo
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Explore the profile of Lauren C Tantalo including associated specialties, affiliations and a list of published articles.
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36
Citations
611
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Recent Articles
1.
Grillova L, Romeis E, Lieberman N, Tantalo L, Xu L, Molini B, et al.
Mol Microbiol
. 2024 Aug;
122(4):455-464.
PMID: 39115038
The recently discovered methodologies to cultivate and genetically manipulate Treponema pallidum subsp. pallidum (T. pallidum) have significantly helped syphilis research, allowing the in vitro evaluation of antibiotic efficacy, performance of...
2.
Tantalo L, Luetkemeyer A, Luetkemeyer A, Lieberman N, Nunley B, Avendano C, et al.
J Infect Dis
. 2024 Jul;
PMID: 39067061
Doxycycline post-exposure prophylaxis (doxy-PEP) could significantly reduce syphilis incidence. However, the increase in intermittent doxycycline usage might select resistant Treponema pallidum (T. pallidum) strains. To assess whether resistance to doxycycline...
3.
Tantalo L, Luetkemeyer A, Lieberman N, Nunley B, Avendano C, Greninger A, et al.
bioRxiv
. 2024 Jul;
PMID: 38979216
Doxycycline post-exposure prophylaxis (doxy-PEP) could significantly reduce syphilis incidence. However, the increase in intermittent doxycycline usage might select resistant ( ) strains. To assess whether resistance to doxycycline could be...
4.
Reid T, Godornes C, Campbell V, Laing K, Tantalo L, Gomez A, et al.
J Infect Dis
. 2024 Jun;
230(2):281-292.
PMID: 38932740
Background: Histologic and serologic studies suggest the induction of local and systemic Treponema pallidum-specific CD4+ T-cell responses to T. pallidum infection. We hypothesized that T. pallidum-specific CD4+ T cells are...
5.
Bright New Resources for Syphilis Research: Genetically Encoded Fluorescent Tags for and Sf1Ep Cells
Grillova L, Romeis E, Lieberman N, Tantalo L, Xu L, Molini B, et al.
bioRxiv
. 2024 Jun;
PMID: 38854070
Graphical Abstract: By employing genetic engineering, was modified to express GFP, and Sf1Ep cells to express mCherry on the cytoplasmic membrane and BFP in the nucleus. These new resources for...
6.
Reid T, Godornes C, Campbell V, Laing K, Tantalo L, Gomez A, et al.
bioRxiv
. 2024 Mar;
PMID: 38464313
Background: Histologic and serologic studies suggest the induction of local and systemic ( )-specific CD4+ T cell responses to infection. We hypothesized that -specific CD4+ T cells are detectable in...
7.
Tantalo L, Lieberman N, Perez-Mana C, Suner C, Vall Mayans M, Ubals M, et al.
Lancet Microbe
. 2023 Oct;
4(12):e994-e1004.
PMID: 37827185
Background: The increasing incidence of syphilis and the limitations of first-line treatment with penicillin, particularly in neurosyphilis, neonatal syphilis, and pregnancy, highlight the need to expand the therapeutic repertoire for...
8.
Romeis E, Lieberman N, Molini B, Tantalo L, Chung B, Phung Q, et al.
PLoS Pathog
. 2023 Mar;
19(3):e1011259.
PMID: 36940224
Background: The TprK protein of the syphilis agent, Treponema pallidum subsp. pallidum (T. pallidum), undergoes antigenic variation in seven discrete variable (V) regions via non-reciprocal segmental gene conversion. These recombination...
9.
Tantalo L, Molini B, Bose M, Klausner J, Giacani L
Sex Transm Dis
. 2023 Feb;
50(3):180-183.
PMID: 36730573
Isolation of Treponema pallidum subsp. pallidum strains still relies on rabbit intratesticular inoculation of clinical samples. In this article, we report an alternative isolation approach based on the inoculation of...
10.
Romeis E, Lieberman N, Molini B, Tantalo L, Chung B, Phung Q, et al.
bioRxiv
. 2023 Jan;
PMID: 36711914
Background: The TprK protein of the syphilis agent, subsp. ( ), undergoes antigenic variation in seven discrete variable (V) regions via non-reciprocal segmental gene conversion. These recombination events transfer information...