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Laura Vanagas

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Articles 18
Citations 135
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Recent Articles
1.
Vanagas L, Cristaldi C, La Bella G, Ganuza A, Angel S, Alonso A
Sci Rep . 2024 Nov; 14(1):27687. PMID: 39533086
Long non-coding RNAs (lncRNAs) have emerged as significant players in diverse cellular processes, including cell differentiation. Advancements in computational methodologies have facilitated the prediction of lncRNA functions, enabling insights even...
2.
Vanagas L, Alonso A, Angel S
Gene . 2024 Sep; 933:148924. PMID: 39245231
Toxoplasma gondii is an obligate intracellular parasite with sexual reproduction in the intestinal epithelium of felines. The depletion of two gene repressors, AP2XI-2 and AP2XII-1, induces merozoite formation and gene...
3.
Angel S, Vanagas L, Alonso A
Mol Biochem Parasitol . 2024 Feb; 258:111615. PMID: 38354788
Toxoplasma has high host flexibility, infecting all nucleated cells of mammals and birds. This implies that during its infective process the parasite must constantly adapt to different environmental situations, which...
4.
Deng B, Vanagas L, Alonso A, Angel S
Pathogens . 2024 Jan; 13(1). PMID: 38251340
, a protozoan parasite with the ability to infect various warm-blooded vertebrates, including humans, is the causative agent of toxoplasmosis. This infection poses significant risks, leading to severe complications in...
5.
Cristaldi C, Saldarriaga Cartagena A, Ganuza A, Sullivan Jr W, Angel S, Vanagas L
Int J Parasitol Drugs Drug Resist . 2023 Dec; 23:120-129. PMID: 38043188
Toxoplasma gondii is an obligate intracellular parasite in the phylum Apicomplexa that causes toxoplasmosis in humans and animals worldwide. Despite its prevalence, there is currently no effective vaccine or treatment...
6.
Vanagas L, Munoz D, Cristaldi C, Ganuza A, Najera R, Bonardi M, et al.
Biochim Biophys Acta Gene Regul Mech . 2023 May; 1866(3):194943. PMID: 37217032
Through regulation of DNA packaging, histone proteins are fundamental to a wide array of biological processes. A variety of post-translational modifications (PTMs), including acetylation, constitute a proposed histone code that...
7.
Munera Lopez J, Alonso A, Figueras M, Saldarriaga Cartagena A, Hortua Triana M, Diambra L, et al.
Proteomes . 2023 Mar; 11(1). PMID: 36976888
is an obligate intracellular apicomplexan that causes toxoplasmosis in humans and animals. Central to its dissemination and pathogenicity is the ability to rapidly divide in the tachyzoite stage and infect...
8.
Vanagas L, Munoz D, Cristaldi C, Ganuza A, Najera R, Bonardi M, et al.
bioRxiv . 2023 Feb; PMID: 36824796
Through regulation of DNA packaging, histone proteins are fundamental to a wide array of biological processes. A variety of post-translational modifications (PTMs), including acetylation, constitute a proposed histone code that...
9.
Contreras S, Zambrano Siri R, Rivera E, Cristaldi C, Kamenetzky L, Kim K, et al.
Epigenomes . 2022 Sep; 6(3). PMID: 36135316
Subtelomeres (ST) are chromosome regions that separate telomeres from euchromatin and play relevant roles in various biological processes of the cell. While their functions are conserved, ST structure and genetic...
10.
Nardelli S, de Monerri N, Vanagas L, Wang X, Tampaki Z, Sullivan Jr W, et al.
BMC Genomics . 2022 Feb; 23(1):128. PMID: 35164683
Background: Toxoplasma gondii is a protozoan parasite that differentiates from acute tachyzoite stages to latent bradyzoite forms in response to environmental cues that modify the epigenome. We studied the distribution...