Laura Schmitt
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Explore the profile of Laura Schmitt including associated specialties, affiliations and a list of published articles.
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41
Citations
119
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Recent Articles
1.
Krings K, Wassenberg T, Cea-Medina P, Schmitt L, Lechtenberg I, Llewellyn T, et al.
Molecules
. 2025 Jan;
29(24.
PMID: 39770138
(3-(pyrimidin-4-yl)-7-azaindoles) are synthetic hybrids of the naturally occurring alkaloids and and display a strong cytotoxic potential. We have recently shown that the novel derivative is highly cytotoxic in several lymphoma...
2.
Schmitt L, Krings K, Wolsing A, Buque X, Zimmermann M, Flores-Romero H, et al.
Cell Commun Signal
. 2024 Nov;
22(1):541.
PMID: 39533399
Targeting mitochondrial metabolism represents a promising approach for cancer treatment. Here, we investigated the mitotoxic potential of the polybrominated diphenyl ether bromoxib, a natural compound isolated from the marine sponge...
3.
Scherer B, Bogun L, Koch A, Jager P, Maus U, Schmitt L, et al.
Arch Toxicol
. 2024 Nov;
99(1):393-406.
PMID: 39531065
While antineoplastic therapies aim to specifically target cancer cells, they may also exert adverse effects on healthy tissues, like healthy hematopoietic stem and progenitor cells (HSPC), leading to hematotoxicity as...
4.
Zwolski C, Rethorn T, Thomas S, Goodway J, Paterno M, Quatman-Yates C, et al.
Int J Sports Phys Ther
. 2024 Sep;
19(9):1052-1067.
PMID: 39267628
Background: Despite evidence of alarming declines in physical activity levels after anterior cruciate ligament reconstruction (ACLR), very little is known about how young athletes perceive their experiences with engagement in...
5.
Schmitt L, Hoppe J, Cea-Medina P, Bruch P, Krings K, Lechtenberg I, et al.
Cell Death Discov
. 2024 Jun;
10(1):279.
PMID: 38862521
A key feature of cancer is the disruption of cell cycle regulation, which is characterized by the selective and abnormal activation of cyclin-dependent kinases (CDKs). Consequently, targeting CDKs via meriolins...
6.
Schmitt L, Lechtenberg I, Driessen D, Flores-Romero H, Skowron M, Sekeres M, et al.
Cell Death Discov
. 2024 Mar;
10(1):125.
PMID: 38461295
Meriolin derivatives represent a new class of kinase inhibitors with a pronounced cytotoxic potential. Here, we investigated a newly synthesized meriolin derivative (termed meriolin 16) that displayed a strong apoptotic...
7.
Weber F, Weber A, Schmitt L, Lechtenberg I, Greb J, Henssen B, et al.
Chemistry
. 2024 Feb;
30(25):e202400559.
PMID: 38411573
Dimeric naphthopyranones are known to be biologically active, however, for the corresponding monomeric naphthopyranones this information is still elusive. Here the first enantioselective total synthesis of semi-viriditoxic acid as well...
8.
Schmitt L, Pfirrmann C, Buck F, Hany T, Rosskopf A
Skeletal Radiol
. 2024 Jan;
53(7):1269-1278.
PMID: 38206356
Purpose: To evaluate the distribution of intra- and extraarticular MRI findings in children and adolescents with clinically suspected intraarticular cause of hip pain in order to assess the need for...
9.
Pollock N, Fernandes J, Woodfield J, Moussa E, Hlavay B, Branton W, et al.
Brain Behav Immun
. 2023 Nov;
115:374-393.
PMID: 37914099
Neuroinflammation coupled with demyelination and neuro-axonal damage in the central nervous system (CNS) contribute to disease advancement in progressive multiple sclerosis (P-MS). Inflammasome activation accompanied by proteolytic cleavage of gasdermin...
10.
Selhorst M, Hoehn J, Schmitt L, Benedict J, Fernandez-Fernandez A
J Orthop Sports Phys Ther
. 2023 Sep;
53(10):634–642.
PMID: 37706686
To test whether a series of brief, psychologically informed educational videos added to physical therapy improved function among adolescents with patellofemoral pain. The secondary aims were to assess pain and...