Laura S Collins
Overview
Explore the profile of Laura S Collins including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
347
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0
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Recent Articles
1.
Andrianov V, Gailite V, Lola D, Loza E, Semenikhina V, Kalvinsh I, et al.
Eur J Med Chem
. 2008 Aug;
44(3):1067-85.
PMID: 18672316
Enzymatic inhibition of histone deacetylase (HDAC) activity is emerging as an innovative and effective approach for the treatment of cancer. A series of novel amide derivatives have been synthesized and...
2.
Khan N, Jeffers M, Kumar S, Hackett C, Boldog F, Khramtsov N, et al.
Biochem J
. 2007 Sep;
409(2):581-9.
PMID: 17868033
The human HDAC (histone deacetylase) family, a well-validated anticancer target, plays a key role in the control of gene expression through regulation of transcription. While HDACs can be subdivided into...
3.
Tumber A, Collins L, Petersen K, Thougaard A, Christiansen S, Dejligbjerg M, et al.
Cancer Chemother Pharmacol
. 2006 Nov;
60(2):275-83.
PMID: 17124594
Purpose: Histone deacetylase inhibitors (HDACi) inhibit the growth of cancer cells, and combinations of HDACi with established chemotherapeutics can lead to synergistic effects. We have investigated effects of PXD101 (HDACi...