Laura Marcu
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Explore the profile of Laura Marcu including associated specialties, affiliations and a list of published articles.
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128
Citations
2175
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Recent Articles
1.
Liu X, Bec J, Zhou X, Garcia A, Marcu L
Opt Lett
. 2025 Jan;
50(3):900-903.
PMID: 39888783
We report a multispectral laser-scanning pulse-sampling fluorescence lifetime imaging (LSPS-FLIm) system designed for rapid, high-resolution imaging of large tissue specimens. This system provides a substantial imaging field of view (FoV)...
2.
Dave D, Garcia A, Kraft L, Marcu L, Pereira C
J Hand Surg Am
. 2025 Jan;
PMID: 39755964
Purpose: Current technologies to define the zone of acute peripheral nerve injury intraoperatively are limited by surgical experience, time, cumbersome electrodiagnostic equipment, and interpreter reliability. In this pilot study, we...
3.
Yuan N, Hassan M, Ehrlich K, Weyers B, Biddle G, Ivanovic V, et al.
Diagnostics (Basel)
. 2024 Sep;
14(18).
PMID: 39335776
: Early detection and accurate diagnosis of lymph node metastasis (LNM) in head and neck cancer (HNC) are crucial for enhancing patient prognosis and survival rates. Current imaging methods have...
4.
Tufaro V, Jaffer F, Serruys P, Onuma Y, van der Steen A, Stone G, et al.
JACC Cardiovasc Interv
. 2024 Sep;
17(17):1963-1979.
PMID: 39260958
Intravascular ultrasound and optical coherence tomography are used with increasing frequency for the care of coronary patients and in research studies. These imaging tools can identify culprit lesions in acute...
5.
Bec J, Zhou X, Villiger M, Southard J, Bouma B, Marcu L
Biomed Opt Express
. 2024 Apr;
15(4):2114-2132.
PMID: 38633060
The clinical management of coronary artery disease and the prevention of acute coronary syndromes require knowledge of the underlying atherosclerotic plaque pathobiology. Hybrid imaging modalities capable of comprehensive assessment of...
6.
Zhou X, Bec J, Ehrlich K, Garcia A, Marcu L
Opt Lett
. 2023 Sep;
48(17):4578-4581.
PMID: 37656559
This Letter presents an experimental study comparing the photon rate and photon economy of pulse sampling fluorescence lifetime imaging (PS-FLIm) with the conventional time-correlated single photon counting (TCSPC) technique. We...
7.
Alfonso-Garcia A, Anbunesan S, Bec J, Lee H, Jin L, Bloch O, et al.
Biomed Opt Express
. 2023 May;
14(5):2196-2208.
PMID: 37206147
Challenges in identifying a glioblastoma's infiltrative edge during neurosurgical procedures result in rapid recurrence. A label-free fluorescence lifetime imaging (FLIm) device was used to evaluate glioblastoma's infiltrative edge in 15...
8.
Bou-Samra P, Muhammad N, Chang A, Karsalia R, Azari F, Kennedy G, et al.
J Biomed Opt
. 2023 May;
28(5):050901.
PMID: 37193364
Significance: This third biennial intraoperative molecular imaging (IMI) conference shows how optical contrast agents have been applied to develop clinically significant endpoints that improve precision cancer surgery. Aim: National and...
9.
Hassan M, Weyers B, Bec J, Fereidouni F, Qi J, Gui D, et al.
IEEE Trans Biomed Eng
. 2023 Apr;
70(10):2863-2873.
PMID: 37043314
Intraoperative identification of head and neck cancer tissue is essential to achieve complete tumor resection and mitigate tumor recurrence. Mesoscopic fluorescence lifetime imaging (FLIm) of intrinsic tissue fluorophores emission has...
10.
Zhou X, Haudenschild A, Li C, Marcu L
J Biomed Opt
. 2023 Feb;
28(2):026003.
PMID: 36818585
Significance: Cartilage tissue engineering is a promising strategy for effective curative therapies for treatment of osteoarthritis. However, tissue engineers depend predominantly on time-consuming, expensive, and destructive techniques as quality control...