Laura Hernandez-Lagunas
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Explore the profile of Laura Hernandez-Lagunas including associated specialties, affiliations and a list of published articles.
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24
Citations
405
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Recent Articles
1.
Elajaili H, Hernandez-Lagunas L, Harris P, Sparagna G, Jonscher R, Ohlstrom D, et al.
Adv Redox Res
. 2024 Jan;
5.
PMID: 38273965
Extracellular superoxide dismutase (EC-SOD) is highly expressed in the lung and vasculature. A common human single nucleotide polymorphism (SNP) in the matrix binding region of EC-SOD leads to a single...
2.
Ohlstrom D, Sul C, Vohwinkel C, Hernandez-Lagunas L, Karimpour-Fard A, Mourani P, et al.
Sci Rep
. 2022 Aug;
12(1):14560.
PMID: 36028738
Acute respiratory distress syndrome is a heterogeneous pathophysiological process responsible for significant morbidity and mortality in pediatric intensive care patients. Diagnosis is defined by clinical characteristics that identify the syndrome...
3.
Ohlstrom D, Hernandez-Lagunas L, Garcia A, Allawzi A, Karimpour-Fard A, Sucharov C, et al.
Physiol Genomics
. 2020 May;
52(6):245-254.
PMID: 32421439
Oxidative stress is a key contributor to the development of dysregulated inflammation in acute lung injury (ALI). A naturally occurring single nucleotide polymorphism in the key extracellular antioxidant enzyme, extracellular...
4.
Tseng V, Ni K, Allawzi A, Prohaska C, Hernandez-Lagunas L, Elajaili H, et al.
Sci Rep
. 2020 Jan;
10(1):280.
PMID: 31937874
Chronic hypoxia leads to pathologic remodeling of the pulmonary vasculature and pulmonary hypertension (PH). The antioxidant enzyme extracellular superoxide dismutase (SOD3) protects against hypoxia-induced PH. Hyaluronan (HA), a ubiquitous glycosaminoglycan...
5.
Allawzi A, McDermott I, Delaney C, Nguyen K, Banimostafa L, Trumpie A, et al.
FASEB J
. 2019 Sep;
33(12):13465-13475.
PMID: 31560857
A human single nucleotide polymorphism (SNP) in the matrix-binding domain of extracellular superoxide dismutase (EC-SOD), with arginine to glycine substitution at position 213 (R213G), redistributes EC-SOD from the matrix into...
6.
Elajaili H, Hernandez-Lagunas L, Ranguelova K, Dikalov S, Nozik-Grayck E
J Vis Exp
. 2019 Jan;
(143).
PMID: 30688300
The accurate and specific detection of reactive oxygen species (ROS) in different cellular and tissue compartments is essential to the study of redox-regulated signaling in biological settings. Electron paramagnetic resonance...
7.
Patil M, Upadhyay A, Hernandez-Lagunas L, Good R, Carpenter T, Sucharov C, et al.
Artif Cells Nanomed Biotechnol
. 2018 Nov;
46(sup3):S1059-S1066.
PMID: 30450979
Ephrin type-A receptor 2 (EphA2) is a transmembrane receptor which is upregulated in injured lungs, including those treated with bleomycin. YSA peptide (YSAYPDSVPMMS), a mimic of ephrin ligands, binds to...
8.
Sen R, Pezoa S, Shull L, Hernandez-Lagunas L, Niswander L, Artinger K
J Dev Biol
. 2018 Nov;
6(4).
PMID: 30424580
Cranial neural crest cells undergo cellular growth, patterning, and differentiation within the branchial arches to form cartilage and bone, resulting in a precise pattern of skeletal elements forming the craniofacial...
9.
Good R, Hernandez-Lagunas L, Allawzi A, Maltzahn J, Vohwinkel C, Upadhyay A, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Jul;
315(4):L584-L594.
PMID: 30024304
MicroRNAs (miRNAs) are noncoding RNAs that regulate gene expression in many diseases, although the contribution of miRNAs to the pathophysiology of lung injury remains obscure. We hypothesized that dysregulation of...
10.
Garcia A, Allawzi A, Tatman P, Hernandez-Lagunas L, Swain K, Mouradian G, et al.
Physiol Genomics
. 2018 Jul;
50(9):807-816.
PMID: 30004839
Extracellular superoxide dismutase (EC-SOD), one of three mammalian SOD isoforms, is the sole extracellular enzymatic defense against superoxide. A known human single nucleotide polymorphism (SNP) in the matrix-binding domain of...