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Laura Graciotti

Explore the profile of Laura Graciotti including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 585
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Recent Articles
1.
Prattichizzo F, Ceriello A, Pellegrini V, La Grotta R, Graciotti L, Olivieri F, et al.
Eur Heart J . 2024 Sep; 45(38):4099-4110. PMID: 39240674
Emerging evidence indicates that chemical exposures in the environment are overlooked drivers of cardiovascular diseases (CVD). Recent evidence suggests that micro- and nanoplastic (MNP) particles derived largely from the chemical...
2.
Bastioli G, Piccirillo S, Graciotti L, Carone M, Sprega G, Taoussi O, et al.
Cells . 2024 Aug; 13(15. PMID: 39120330
Parkinson's disease (PD) is a progressive neurodegenerative disorder that lacks effective treatment strategies to halt or delay its progression. The homeostasis of Ca ions is crucial for ensuring optimal cellular...
3.
Licini C, Morroni G, Lucarini G, Vitto V, Orlando F, Missiroli S, et al.
Cell Death Dis . 2024 Jun; 15(6):407. PMID: 38862500
Methicillin-resistant Staphylococcus aureus (MRSA) is the most common causative agent of acute bacterial skin and skin-structure infections (ABSSSI), one of the major challenges to the health system worldwide. Although the...
4.
Marfella R, Prattichizzo F, Sardu C, Fulgenzi G, Graciotti L, Spadoni T, et al.
N Engl J Med . 2024 Mar; 390(10):900-910. PMID: 38446676
Background: Microplastics and nanoplastics (MNPs) are emerging as a potential risk factor for cardiovascular disease in preclinical studies. Direct evidence that this risk extends to humans is lacking. Methods: We...
5.
Alesi N, Khabibullin D, Rosenthal D, Akl E, Cory P, Alchoueiry M, et al.
Nat Commun . 2024 Jan; 15(1):406. PMID: 38195686
Tuberous Sclerosis Complex (TSC) is caused by TSC1 or TSC2 mutations, leading to hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) and lesions  in multiple organs including lung (lymphangioleiomyomatosis)...
6.
Giuliani A, Giudetti A, Vergara D, Del Coco L, Ramini D, Caccese S, et al.
Antioxidants (Basel) . 2023 Nov; 12(11). PMID: 38001810
Cellular senescence is closely linked to endothelial dysfunction, a key factor in age-related vascular diseases. Senescent endothelial cells exhibit a proinflammatory phenotype known as SASP, leading to chronic inflammation (inflammaging)...
7.
Giuliani A, Sabbatinelli J, Amatori S, Graciotti L, Silvestrini A, Matacchione G, et al.
Cell Mol Life Sci . 2023 Feb; 80(3):75. PMID: 36847916
Methyl-CpG binding protein 2 (MeCP2) is a ubiquitous transcriptional regulator. The study of this protein has been mainly focused on the central nervous system because alterations of its expression are...
8.
Giuliani A, Montesanto A, Matacchione G, Graciotti L, Ramini D, Protic O, et al.
Int J Mol Sci . 2022 May; 23(10). PMID: 35628426
Disorders of lipoprotein metabolism are among the major risk factors for cardiovascular disease (CVD) development. Single nucleotide polymorphisms (SNPs) have been associated with the individual variability in blood lipid profile...
9.
Bronte G, Procopio A, Graciotti L
Crit Rev Oncol Hematol . 2022 May; 174:103698. PMID: 35525390
The high mortality rate of malignant pleural mesothelioma led to study the mechanisms for chemoresistance. The cancer stem cell (CSC) model has been proposed to explain chemoresistance. CSCs are characterized...
10.
Monaco F, De Conti L, Vodret S, Zanotta N, Comar M, Manzotti S, et al.
Transl Oncol . 2022 Mar; 20:101400. PMID: 35334283
Malignant pleural mesothelioma (MPM) is an aggressive tumour resistant to treatments. It has been postulated that cancer stem cells (CSCs) persist in tumours causing relapse after multimodality treatment. In the...