Laura Geffner
Overview
Explore the profile of Laura Geffner including associated specialties, affiliations and a list of published articles.
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9
Citations
138
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Recent Articles
1.
Geffner L, Basile J, Yokobori N, Kviatcovsky D, Sabio y Garcia C, Ritacco V, et al.
PLoS One
. 2014 May;
9(5):e97837.
PMID: 24836916
In human tuberculosis (TB), CD8+ T cells contribute to host defense by the release of Th1 cytokines and the direct killing of Mycobacterium tuberculosis (Mtb)-infected macrophages via granule exocytosis pathway...
2.
Garbossa G, Buyayisqui M, Geffner L, Lopez Arias L, de la Fourniere S, Haedo A, et al.
Pathog Glob Health
. 2013 May;
107(3):141-52.
PMID: 23683369
Health inequities are a common problem for all countries and are the result of not only adverse social conditions but also poor public policies. Today chronic diseases represent the most...
3.
Yokobori N, Lopez B, Geffner L, Sabio y Garcia C, Schierloh P, Barrera L, et al.
Infect Genet Evol
. 2013 Jan;
16:151-6.
PMID: 23352891
Mycobacterium tuberculosis has a considerable degree of genetic variability resulting in different epidemiology and disease outcomes. We evaluated the pathogen-host cell interaction of two genetically closely-related multidrug-resistant M. tuberculosis strains...
4.
Yokobori N, Sabio Y Garcia C, Geffner L, Schierloh P, Lopez B, Ritacco V, et al.
FEMS Immunol Med Microbiol
. 2012 Aug;
66(3):363-71.
PMID: 22889125
Some multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) genotypes are the cause of large outbreaks, including strain M identified in Argentina. In contrast, its kin strain 410 has only caused a single...
5.
Balboa L, Romero M, Basile J, Sabio Y Garcia C, Schierloh P, Yokobori N, et al.
J Leukoc Biol
. 2011 Apr;
90(1):69-75.
PMID: 21454357
The role of CD16(-) and CD16(+) Mo subsets in human TB remains unknown. Our aim was to characterize Mo subsets from TB patients and to assess whether the inflammatory milieu...
6.
Balboa L, Romero M, Yokobori N, Schierloh P, Geffner L, Basile J, et al.
Immunol Cell Biol
. 2010 Mar;
88(7):716-26.
PMID: 20212510
During a chronic infection such as tuberculosis, the pool of tissue dendritic cells (DC) must be renewed by recruitment of both circulating DC progenitors and monocytes (Mo). However, the microenvironment...
7.
Geffner L, Yokobori N, Basile J, Schierloh P, Balboa L, Romero M, et al.
Infect Immun
. 2009 Sep;
77(11):5025-34.
PMID: 19720756
In Argentina, multidrug-resistant tuberculosis (MDR-TB) outbreaks emerged among hospitalized patients with AIDS in the early 1990s and thereafter disseminated to the immunocompetent community. Epidemiological, bacteriological, and genotyping data allowed the...
8.
Schierloh P, Yokobori N, Geffner L, Balboa L, Romero M, Musella R, et al.
Eur J Immunol
. 2009 Aug;
39(9):2450-8.
PMID: 19714575
Tuberculous pleurisy, one of the most common manifestations of extrapulmonary tuberculosis, is characterized by a T-cell-mediated hypersensitivity reaction along with a Th1 immune profile. In this study, we investigated functional...
9.
Schierloh P, Yokobori N, Aleman M, Landoni V, Geffner L, Musella R, et al.
Infect Immun
. 2007 Aug;
75(11):5325-37.
PMID: 17709420
Tuberculous pleurisy allows the study of human cells at the site of active Mycobacterium tuberculosis infection. In this study, we found that among pleural fluid (PF) lymphocytes, natural killer (NK)...