Laura Fernandez-Martin
Overview
Explore the profile of Laura Fernandez-Martin including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
267
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0
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Recent Articles
1.
Labat-de-Hoz L, Fernandez-Martin L, Correas I, Alonso M
Cell Mol Life Sci
. 2024 Jun;
81(1):279.
PMID: 38916773
Mutations in the human INF2 gene cause autosomal dominant focal segmental glomerulosclerosis (FSGS)-a condition characterized by podocyte loss, scarring, and subsequent kidney degeneration. To understand INF2-linked pathogenicity, we examined the...
2.
Labat-de-Hoz L, Comas L, Rubio-Ramos A, Casares-Arias J, Fernandez-Martin L, Pantoja-Uceda D, et al.
Cell Mol Life Sci
. 2022 Oct;
79(11):571.
PMID: 36306014
In INF2-a formin linked to inherited renal and neurological disease in humans-the DID is preceded by a short N-terminal extension of unknown structure and function. INF2 activation is achieved by...
3.
Fernandez-Barrera J, Bernabe-Rubio M, Casares-Arias J, Rangel L, Fernandez-Martin L, Correas I, et al.
J Cell Biol
. 2018 Jan;
217(3):929-944.
PMID: 29321169
The role of formins in microtubules is not well understood. In this study, we have investigated the mechanism by which INF2, a formin mutated in degenerative renal and neurological hereditary...
4.
Marcos-Ramiro B, Garcia-Weber D, Barroso S, Feito J, Ortega M, Cernuda-Morollon E, et al.
J Cell Biol
. 2016 May;
213(3):385-402.
PMID: 27138256
Endothelial barrier dysfunction underlies chronic inflammatory diseases. In searching for new proteins essential to the human endothelial inflammatory response, we have found that the endosomal GTPase RhoB is up-regulated in...
5.
Ventimiglia L, Fernandez-Martin L, Martinez-Alonso E, Anton O, Guerra M, Martinez-Menarguez J, et al.
J Immunol
. 2015 Jun;
195(3):810-4.
PMID: 26109641
Exosomes secreted by T cells play an important role in coordinating the immune response. HIV-1 Nef hijacks the route of exosome secretion of T cells to modulate the functioning of...
6.
Reglero-Real N, Alvarez-Varela A, Cernuda-Morollon E, Feito J, Marcos-Ramiro B, Fernandez-Martin L, et al.
Cell Rep
. 2014 Sep;
8(6):1879-1893.
PMID: 25242329
Loss of apicobasal polarity is a hallmark of epithelial pathologies. Leukocyte infiltration and crosstalk with dysfunctional epithelial barriers are crucial for the inflammatory response. Here, we show that apicobasal architecture...
7.
Aranda J, Reglero-Real N, Marcos-Ramiro B, Ruiz-Saenz A, Fernandez-Martin L, Bernabe-Rubio M, et al.
Mol Biol Cell
. 2012 Dec;
24(4):483-94.
PMID: 23264465
The endothelium maintains a barrier between blood and tissue that becomes more permeable during inflammation. Membrane rafts are ordered assemblies of cholesterol, glycolipids, and proteins that modulate proinflammatory cell signaling...
8.
Fernandez-Martin L, Marcos-Ramiro B, Bigarella C, Graupera M, Cain R, Reglero-Real N, et al.
Arterioscler Thromb Vasc Biol
. 2012 Jun;
32(8):e90-102.
PMID: 22723439
Objective: Endothelial cells provide a barrier between the blood and tissues, which is reduced during inflammation to allow selective passage of molecules and cells. Adherens junctions (AJ) play a central...
9.
Millan J, Cain R, Reglero-Real N, Bigarella C, Marcos-Ramiro B, Fernandez-Martin L, et al.
BMC Biol
. 2010 Feb;
8:11.
PMID: 20122254
Background: Endothelial cell-cell junctions maintain endothelial integrity and regulate vascular morphogenesis and homeostasis. Cell-cell junctions are usually depicted with a linear morphology along the boundaries between adjacent cells and in...