Laura E Benjamin
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Explore the profile of Laura E Benjamin including associated specialties, affiliations and a list of published articles.
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44
Citations
3861
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Recent Articles
1.
Fischl A, Wang X, Falcon B, Almonte-Baldonado R, Bodenmiller D, Evans G, et al.
Mol Cancer Ther
. 2019 Feb;
18(4):856-867.
PMID: 30787172
Inhibition of VEGFR signaling is an effective treatment for renal cell carcinoma, but resistance continues to be a major problem. Recently, the sphingosine phosphate (S1P) signaling pathway has been implicated...
2.
Almonte-Baldonado R, Bravo-Nuevo A, Gerald D, Benjamin L, Prendergast G, Laury-Kleintop L
J Cell Biochem
. 2018 Dec;
120(6):9381-9391.
PMID: 30536763
Neovascularization in cancer or retinopathy is driven by pathological changes that foster abnormal sprouting of endothelial cells. Mouse genetic studies indicate that the stress-induced small GTPase RhoB is dispensable for...
3.
Sitohy B, Chang S, Sciuto T, Masse E, Shen M, Kang P, et al.
Am J Pathol
. 2017 Jul;
187(10):2337-2347.
PMID: 28736316
Tumors induce their heterogeneous vasculature by secreting vascular endothelial growth factor (VEGF)-A. Anti-VEGF/VEGF receptor (VEGFR) drugs treat cancer, but the underlying mechanisms remain unclear. An adenovirus expressing VEGF-A (Ad-VEGF-A) replicates...
4.
Shafique E, Torina A, Reichert K, Colantuono B, Nur N, Ravichandran V, et al.
Cardiovasc Res
. 2017 Jan;
113(2):234-246.
PMID: 28088753
Aims: There are conflicting reports on the role of reactive oxygen species (ROS) i.e. beneficial vs. harmful, in vascular endothelium. Here, we aim to examine whether duration of exposure to...
5.
6.
Holzer T, Fulford A, Reising L, Nedderman D, Zhang X, Benjamin L, et al.
Anticancer Res
. 2016 Jun;
36(7):3277-88.
PMID: 27354584
Background: the vascular endothelial growth factor (VEGF) pathway plays a prominent role in the growth and progression of human cancer, including non-small cell lung carcinoma (NSCLC). The key mediators of...
7.
Nasir A, Reising L, Nedderman D, Fulford A, Uhlik M, Benjamin L, et al.
Anticancer Res
. 2016 Jun;
36(6):2683-96.
PMID: 27272777
Background: The vascular endothelial growth factor (VEGF) pathway plays an important role in growth and progression of human cancer, including colorectal carcinomas (CRC). The key mediators of VEGF signaling are...
8.
Uhlik M, Liu J, Falcon B, Iyer S, Stewart J, Celikkaya H, et al.
Cancer Res
. 2016 May;
76(9):2573-86.
PMID: 27197264
Treatment of metastatic gastric cancer typically involves chemotherapy and monoclonal antibodies targeting HER2 (ERBB2) and VEGFR2 (KDR). However, reliable methods to identify patients who would benefit most from a combination...
9.
ODonnell R, Falcon B, Hanson J, Goldstein W, Perruzzi C, Rafii S, et al.
Cancer Res
. 2016 Jan;
76(3):517-24.
PMID: 26719538
Antiangiogenesis-based cancer therapies, specifically those targeting the VEGF-A/VEGFR2 pathway, have been approved for subsets of solid tumors. However, these therapies result in an increase in hematologic adverse events. We surmised...
10.
Cohen Y, Dafni H, Avni R, Fellus L, Bochner F, Rotkopf R, et al.
Biol Reprod
. 2015 Oct;
94(1):14.
PMID: 26490838
Ovarian tissue cryopreservation and transplantation is one of a few available treatments for fertility preservation in women diagnosed with cancer. Rapid revascularization is essential for reducing hypoxic damage after grafting...