Laura Contreras-Ruiz
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Explore the profile of Laura Contreras-Ruiz including associated specialties, affiliations and a list of published articles.
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22
Citations
497
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Recent Articles
1.
Bhatia U, Tadman S, Rocha A, Rudraboina R, Contreras-Ruiz L, Guinan E
Am J Transplant
. 2024 Jul;
24(11):1968-1978.
PMID: 38992496
In the extensive literature characterizing lymphocyte contributions to transplant-related pathologies including allograft rejection and graft-versus-host disease, T cell-focused investigation has outpaced investigation of B cells. Most B cell-related reports describe...
2.
Guinan E, Contreras-Ruiz L, Crisalli K, Rickert C, Rosales I, Makar R, et al.
Am J Transplant
. 2023 Jul;
23(12):1872-1881.
PMID: 37422112
Regulatory T cells (Tregs) can inhibit cellular immunity in diverse experimental models and have entered early phase clinical trials in autoimmunity and transplantation to assess safety and efficacy. As part...
3.
Shimozawa K, Contreras-Ruiz L, Sousa S, Zhang R, Bhatia U, Crisalli K, et al.
Am J Transplant
. 2021 Sep;
22(2):504-518.
PMID: 34528383
The potential of adoptive cell therapy with regulatory T cells (Tregs) to promote transplant tolerance is under active exploration. However, the impact of specific transplant settings and protocols on Treg...
4.
Logeswaran A, Contreras-Ruiz L, Masli S
Front Immunol
. 2021 Aug;
12:716939.
PMID: 34434198
Conjunctival epithelium forms a barrier between the ocular surface microbial flora and the ocular mucosa. In addition to secreting gel-forming mucins, goblet cells, located in the conjunctival epithelium, help maintain...
5.
Sawitzki B, Harden P, Reinke P, Moreau A, Hutchinson J, Game D, et al.
Lancet
. 2020 May;
395(10237):1627-1639.
PMID: 32446407
Background: Use of cell-based medicinal products (CBMPs) represents a state-of-the-art approach for reducing general immunosuppression in organ transplantation. We tested multiple regulatory CBMPs in kidney transplant trials to establish the...
6.
Soriano-Romani L, Contreras-Ruiz L, Lopez-Garcia A, Diebold Y, Masli S
Int J Mol Sci
. 2018 Dec;
20(1).
PMID: 30577496
Chronic inflammation of the ocular surface poses a risk of vision impairment. The understanding of the molecular mechanisms that are involved in the inflammatory response is critical to identify novel...
7.
Contreras-Ruiz L, Mir F, Turpie B, Krauss A, Masli S
Exp Eye Res
. 2015 Oct;
143:1-8.
PMID: 26463157
Sjögren's syndrome is an autoimmune disease associated with inflammation of exocrine glands with clinical manifestations of dry eye and dry mouth. Dry eye in this disease involves inflammation of the...
8.
Mir F, Contreras-Ruiz L, Masli S
Immunology
. 2015 Oct;
146(4):547-56.
PMID: 26458493
An important role of transforming growth factor-β (TGF-β) in the development of regulatory T cells is well established. Although integrin-mediated activation of latent TGF-β1 is considered essential for the induction...
9.
Terzulli M, Contreras-Ruiz L, Ruiz L, Kugadas A, Masli S, Gadjeva M
J Ocul Pharmacol Ther
. 2015 Sep;
31(7):413-8.
PMID: 26352162
Purpose: The potential role of commensals as triggering factors that promote inflammation in dry eye disease has not been explored. The objective of this study was to evaluate whether ocular...
10.
Soriano-Romani L, Contreras-Ruiz L, Garcia-Posadas L, Lopez-Garcia A, Masli S, Diebold Y
J Ocul Pharmacol Ther
. 2015 Jul;
31(7):419-28.
PMID: 26154920
Purpose: Increased expression of transforming growth factor-β2 (TGF-β2) is reported in the conjunctiva of dry eye patients with no increase of anti-inflammatory activity of TGF-β2. Our aim was to compare...