Laura C Bell
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Explore the profile of Laura C Bell including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Anil A, Stokes A, Chao R, Hu L, Alhilali L, Karis J, et al.
Front Oncol
. 2023 Feb;
13:1046629.
PMID: 36733305
Background: Relative cerebral blood volume (rCBV) obtained from dynamic susceptibility contrast (DSC) MRI is widely used to distinguish high grade glioma recurrence from post treatment radiation effects (PTRE). Application of...
12.
Griffiths D, Law L, Young C, Fuentes A, Truran S, Karamanova N, et al.
J Neurotrauma
. 2022 May;
39(19-20):1429-1441.
PMID: 35593008
Severe traumatic brain injury (TBI) results in cognitive dysfunction in part due to vascular perturbations. In contrast, the long-term vasculo-cognitive pathophysiology of mild TBI (mTBI) remains unknown. We evaluated mTBI...
13.
McGarry S, Brehler M, Bukowy J, Lowman A, Bobholz S, Duenweg S, et al.
J Magn Reson Imaging
. 2021 Nov;
55(6):1745-1758.
PMID: 34767682
Background: Diffusion-weighted imaging (DWI) is commonly used to detect prostate cancer, and a major clinical challenge is differentiating aggressive from indolent disease. Purpose: To compare 14 site-specific parametric fitting implementations...
14.
Bell L, Fuentes A, Healey D, Chao R, Bakkar N, Sirianni R, et al.
Magn Reson Imaging
. 2021 Oct;
85:217-221.
PMID: 34715291
T relaxivity contrast imaging may serve as a potential imaging biomarker for amyotrophic lateral sclerosis (ALS) by noninvasively quantifying the tissue microstructure. In this preliminary longitudinal study, we investigated the...
15.
Stokes A, Bergamino M, Alhilali L, Hu L, Karis J, Baxter L, et al.
J Cereb Blood Flow Metab
. 2021 Aug;
41(12):3378-3390.
PMID: 34415211
Relative cerebral blood volume (rCBV) obtained from dynamic susceptibility contrast (DSC) MRI is adversely impacted by contrast agent leakage in brain tumors. Using simulations, we previously demonstrated that multi-echo DSC-MRI...
16.
Stokes A, Ragunathan S, Robison R, Fuentes A, Bell L, Karis J, et al.
Magn Reson Med
. 2021 Jul;
86(6):3082-3095.
PMID: 34288112
Purpose: The purpose of this study was to develop a spiral-based combined spin- and gradient-echo (spiral-SAGE) method for simultaneous dynamic contrast-enhanced (DCE-MRI) and dynamic susceptibility contrast MRI (DSC-MRI). Methods: Using...
17.
Ragunathan S, Bell L, Semmineh N, Stokes A, Shefner J, Bowser R, et al.
Tomography
. 2021 Jun;
7(2):169-179.
PMID: 34062974
(1) Background: This work characterizes the sensitivity of magnetic resonance-based Relaxivity Contrast Imaging (RCI) to Amyotrophic Lateral Sclerosis (ALS)-induced changes in myofiber microstructure. Transverse Relaxivity at Tracer Equilibrium (TRATE), an...
18.
Bell L, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda K, et al.
Tomography
. 2020 Jun;
6(2):203-208.
PMID: 32548297
We have previously characterized the reproducibility of brain tumor relative cerebral blood volume (rCBV) using a dynamic susceptibility contrast magnetic resonance imaging digital reference object across 12 sites using a...
19.
Stokes A, Semmineh N, Nespodzany A, Bell L, Quarles C
Magn Reson Med
. 2019 Aug;
83(1):109-123.
PMID: 31400035
Purpose: Brain tumor dynamic susceptibility contrast (DSC) MRI is adversely impacted by T and contrast agent leakage effects that result in inaccurate hemodynamic metrics. While multi-echo acquisitions remove T leakage...
20.
Bell L, Stokes A, Quarles C
J Magn Reson Imaging
. 2019 Jun;
51(2):547-553.
PMID: 31206948
Background: Dynamic susceptibility contrast (DSC)-MRI analysis pipelines differ across studies and sites, potentially confounding the clinical value and use of the derived biomarkers. Purpose/hypothesis: To investigate how postprocessing steps for...