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Laura Belloni

Explore the profile of Laura Belloni including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 1737
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Recent Articles
11.
Salerno D, Chiodo L, Alfano V, Floriot O, Cottone G, Paturel A, et al.
Gut . 2020 Mar; 69(11):2016-2024. PMID: 32114505
Objective: The HBV HBx regulatory protein is required for transcription from the covalently closed circular DNA (cccDNA) minichromosome and affects the epigenetic control of both viral and host cellular chromatin....
12.
Salpini R, Piermatteo L, Battisti A, Colagrossi L, Aragri M, Yu La Rosa K, et al.
Viruses . 2020 Feb; 12(2). PMID: 32102257
Immune-suppression driven Hepatitis B Virus (HBV)-reactivation poses serious concerns since it occurs in several clinical settings and can result in severe forms of hepatitis. Previous studies showed that HBV strains,...
13.
Di Cocco S, Belloni L, Nunn A, Salerno D, Piconese S, Levrero M, et al.
J Vis Exp . 2019 Aug; (149). PMID: 31380833
Hepatic steatosis represents a metabolic dysfunction that results from an accumulation of triglyceride-containing lipid droplets in hepatocytes. Excessive fat accumulation leads to non-alcoholic fatty liver disease (NAFLD),  which is potentially...
14.
Pediconi N, Salerno D, Lupacchini L, Angrisani A, Peruzzi G, De Smaele E, et al.
Cell Death Dis . 2019 Jul; 10(7):518. PMID: 31285428
Modification of histones by lysine methylation plays a role in many biological processes, and it is dynamically regulated by several histone methyltransferases and demethylases. The polycomb repressive complex contains the...
15.
Belloni L, Di Cocco S, Guerrieri F, Nunn A, Piconese S, Salerno D, et al.
Sci Rep . 2018 Sep; 8(1):13638. PMID: 30206377
Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease. Although genetic predisposition and epigenetic factors contribute to the development of NAFLD, our understanding of the molecular...
16.
Guerrieri F, Belloni L, DAndrea D, Pediconi N, Le Pera L, Testoni B, et al.
BMC Genomics . 2017 Feb; 18(1):184. PMID: 28212627
Background: The Hepatitis B Virus (HBV) HBx regulatory protein is required for HBV replication and involved in HBV-related carcinogenesis. HBx interacts with chromatin modifying enzymes and transcription factors to modulate...
17.
Palumbo G, Scisciani C, Pediconi N, Lupacchini L, Alfaiate D, Guerrieri F, et al.
PLoS One . 2015 Dec; 10(12):e0145555. PMID: 26673164
No abstract available.
18.
Palumbo G, Scisciani C, Pediconi N, Lupacchini L, Alfalate D, Guerrieri F, et al.
PLoS One . 2015 Nov; 10(11):e0142599. PMID: 26580974
The HBV covalently closed circular DNA (cccDNA) is organized as a mini-chromosome in the nuclei of infected hepatocytes by histone and non-histone proteins. Transcription from the cccDNA of the RNA...
19.
Costanzo A, Pediconi N, Narcisi A, Guerrieri F, Belloni L, Fausti F, et al.
FEBS Lett . 2014 Jul; 588(16):2590-9. PMID: 24983500
TP53 belongs to a small gene family that includes, in mammals, two additional paralogs, TP63 and TP73. The p63 and p73 proteins are structurally and functionally similar to p53 and...
20.
Guerrieri F, Belloni L, Pediconi N, Levrero M
Semin Liver Dis . 2013 Jun; 33(2):147-56. PMID: 23749671
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through direct and indirect mechanisms. HBV-DNA integration into the host genome occurs at early steps of clonal tumor expansion and...