Lars van der Veen
Overview
Explore the profile of Lars van der Veen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
4
Citations
10
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Volat F, Medhi R, Maggs L, Deken M, Price A, Andrews L, et al.
Mol Cancer Ther
. 2024 Nov;
24(2):230-241.
PMID: 39570650
Autotaxin (ATX), encoded by ENPP2, is a clinical target in pancreatic ductal adenocarcinoma (PDAC). ATX catalyzes the production of lysophosphatidic acid (LPA), an important regulator within the tumor microenvironment (TME),...
2.
Kalla C, Ott G, Finotello F, Niewola-Staszkowska K, Di Conza G, Lahn M, et al.
Transl Oncol
. 2024 Feb;
43:101857.
PMID: 38412661
Targeting aberrantly expressed kinases in malignant pleural mesothelioma (MPM) is a promising therapeutic strategy. We here investigated the effect of the novel and highly selective Phosphoinositide 3-kinase delta (PI3K-δ) inhibitor...
3.
van der Veen L, Schmitt M, Deken M, Lahn M
Int J Toxicol
. 2023 Sep;
42(6):515-534.
PMID: 37667445
Roginolisib (IOA-244) is a novel, non-ATP competitive phosphoinositide-3-kinase (PI3K) delta inhibitor that regulates Akt/mTOR signaling. Roginolisib was administered once daily to rats and dogs in dose-range finding (DRF) and 4-week...
4.
Johnson Z, Tarantelli C, Civanelli E, Cascione L, Spriano F, Fraser A, et al.
Cancer Res Commun
. 2023 Apr;
3(4):576-591.
PMID: 37066023
Significance: IOA-244 is a first-in-class non-ATP-competitive, PI3Kδ inhibitor with direct antitumor activity correlated with PI3Kδ expression. The ability to modulate T cells, antitumor activity in various models with limited toxicity...