Lars O Nooi
Overview
Explore the profile of Lars O Nooi including associated specialties, affiliations and a list of published articles.
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2
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3
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Recent Articles
1.
Kohabir K, Linthorst J, Nooi L, Brouwer R, Wolthuis R, Sistermans E
Cell Rep Methods
. 2024 Dec;
4(12):100912.
PMID: 39644903
Detection of pathogenic DNA variants is vital in cancer diagnostics and treatment monitoring. While CRISPR-based diagnostics (CRISPRdx) offer promising avenues for cost-effective, rapid, and point-of-care testing, achieving single-nucleotide detection fidelity...
2.
Kohabir K, Nooi L, Brink A, Brakenhoff R, Sistermans E, Wolthuis R
CRISPR J
. 2023 Jan;
6(2):127-139.
PMID: 36637878
Cost-effective and time-efficient detection of oncogenic mutations supports improved presymptomatic cancer diagnostics and post-treatment disease monitoring. Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas12a is an RNA-guided endonuclease that, upon protospacer...