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Lars Klimaschewski

Explore the profile of Lars Klimaschewski including associated specialties, affiliations and a list of published articles. Areas
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Articles 65
Citations 1202
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Recent Articles
1.
Palachai N, Supawat A, Kongsui R, Klimaschewski L, Jittiwat J
Int J Mol Sci . 2025 Mar; 26(5). PMID: 40076473
The rising incidence of ischemic stroke poses significant health and healthcare burdens. Given the limitations of current therapeutic options, there is increasing interest in exploring the potential of galangin, a...
2.
Hausott B, Pircher L, Kind M, Park J, Claus P, Obexer P, et al.
Cells . 2024 Dec; 13(23). PMID: 39682716
The Sprouty (SPRY) proteins are evolutionary conserved modulators of receptor tyrosine kinase (RTK) signaling. SPRY2 inhibits fibroblast growth factor (FGF) signaling, whereas it enhances epidermal growth factor (EGF) signaling through...
3.
Kongsui R, Chanmanee T, Promsrisuk T, Klimaschewski L, Sriraksa N, Jittiwat J, et al.
Heliyon . 2024 Oct; 10(18):e38070. PMID: 39381248
Excitotoxicity-induced oxidative stress results in neuronal cell death. Pink lotus essential oil (PLO) is a concentrated volatile oil from lotus blossoms widely used in traditional medicine. This study aimed to...
4.
Kongsui R, Promsrisuk T, Klimaschewski L, Sriraksa N, Jittiwat J, Thongrong S
F1000Res . 2024 Mar; 12:846. PMID: 38434672
: One of the most common neurodegenerative diseases is Parkinson's disease (PD); PD is characterized by a reduction of neurons containing dopamine in the substantia nigra (SN), which leads to...
5.
Amberger A, Pertoll J, Traunfellner P, Kapferer-Seebacher I, Stoiber H, Klimaschewski L, et al.
Front Immunol . 2023 Mar; 14:1157421. PMID: 36960056
Periodontal Ehlers-Danlos syndrome (pEDS) is an autosomal dominant disorder characterized by early-onset periodontitis leading to premature loss of teeth, lack of attached gingiva and thin and fragile gums leading to...
6.
Hausott B, Glueckert R, Schrott-Fischer A, Klimaschewski L
Cells . 2022 May; 11(9). PMID: 35563843
Intracellular signal transduction in response to growth factor receptor activation is a fundamental process during the regeneration of the nervous system. In this context, intracellular inhibitors of neuronal growth factor...
7.
Freilinger M, Klimaschewski L, Brenner E
Ann Anat . 2022 Jan; 241:151890. PMID: 35085704
As elsewhere, the cadavers of Nazi victims were used at the 'Alpenunversität Innsbruck' for the education of medical students. They were also used by members of the Institute of Anatomy...
8.
Skukan L, Brezak M, Ister R, Klimaschewski L, Vojta A, Zoldos V, et al.
J Cereb Blood Flow Metab . 2021 Aug; 42(2):219-236. PMID: 34427147
Due to the limited therapeutic options after ischemic stroke, gene therapy has emerged as a promising choice, especially with recent advances in viral vector delivery systems. Therefore, we aimed to...
9.
Klimaschewski L, Claus P
Mol Neurobiol . 2021 Apr; 58(8):3884-3902. PMID: 33860438
Fibroblast growth factors (FGFs) act as key signalling molecules in brain development, maintenance, and repair. They influence the intricate relationship between myelinating cells and axons as well as the association...
10.
Jamsuwan S, Klimaschewski L, Hausott B
Front Cell Neurosci . 2020 Feb; 13:583. PMID: 32038175
Sprouty2 (Spry2) and phosphatase and tensin homolog deleted on chromosome 10 (PTEN) are both well-established regulators of receptor tyrosine kinase (RTK) signaling, and knockdown of Spry2 or PTEN enhances axon...