Lars Edvinsson
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Explore the profile of Lars Edvinsson including associated specialties, affiliations and a list of published articles.
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348
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5879
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Recent Articles
1.
Pellesi L, Edvinsson L
J Headache Pain
. 2025 Jan;
26(1):22.
PMID: 39891050
Substance P, previously dismissed as a therapeutic target for migraine due to the failure of neurokinin-1 receptor antagonists, warrants renewed attention. Building on the success of therapies targeting the calcitonin...
2.
Edvinsson J, Grubor I, Maddahi A, Edvinsson L
J Headache Pain
. 2024 Dec;
25(1):216.
PMID: 39663536
Background: The purpose of this study was to examine whether there are sex differences in vasomotor responses and receptor localization of hormones and neuropeptides with relevance to migraine (vasopressin, oxytocin,...
3.
Edvinsson L
Expert Rev Neurother
. 2024 Dec;
24(12):1141-1155.
PMID: 39620902
Introduction: Rimegepant is an oral small-molecule calcitonin gene-related peptide receptor antagonist approved in several countries for acute treatment of migraine and preventive treatment of episodic migraine in adults. This review...
4.
Maddahi A, Edvinsson J, Edvinsson L
J Headache Pain
. 2024 Nov;
25(1):193.
PMID: 39516766
Background: Calcitonin gene-related peptide (CGRP) is part of the calcitonin peptide family, which includes calcitonin (CT), amylin (AMY), and adrenomedullin (ADM). CGRP and its receptor are highly present in the...
5.
Karsan N, Edvinsson L, Vecsei L, Goadsby P
Ann Clin Transl Neurol
. 2024 Jun;
11(7):1654-1668.
PMID: 38887982
Objective: Migraine is a complex and disabling neurological disorder. Recent years have witnessed the development and emergence of novel treatments for the condition, namely those targeting calcitonin gene-related peptide (CGRP)....
6.
Edvinsson J, Ran C, Jennysdotter Olofsgard F, Steinberg A, Edvinsson L, Belin A
J Headache Pain
. 2024 May;
25(1):85.
PMID: 38783191
The trigeminal system is key to the pathophysiology of migraine and cluster headache, two primary headache disorders that share many features. Recently, MER proto-oncogene tyrosine kinase (MERTK), a cell surface...
7.
Reducha P, Bomers J, Edvinsson L, Haanes K
Headache
. 2024 May;
64(6):652-662.
PMID: 38700141
Objective: Migraine, a prevalent and debilitating disease, involves complex pathophysiology possibly including inflammation and heightened pain sensitivity. The current study utilized the complete Freund's adjuvant (CFA) model of inflammation, with...
8.
Bomers J, Holm A, Kazantzi S, Edvinsson L, Mathiesen T, Haanes K
J Stroke Cerebrovasc Dis
. 2024 Apr;
33(7):107728.
PMID: 38643942
Objectives: Subarachnoid haemorrhage (SAH) carries a high burden of morbidity and mortality. One in three patients develop vasospasm, which is associated with Delayed Cerebral Ischemia. The pathophysiology includes vasoconstrictor receptor...
9.
Godley 3rd F, Meitzen J, Nahman-Averbuch H, ONeal M, Yeomans D, Santoro N, et al.
J Pers Med
. 2024 Feb;
14(2).
PMID: 38392617
Sex hormones and migraine are closely interlinked. Women report higher levels of migraine symptoms during periods of sex hormone fluctuation, particularly during puberty, pregnancy, and perimenopause. Ovarian steroids, such as...
10.
Edvinsson L, Krause D
Transl Stroke Res
. 2024 Feb;
PMID: 38334872
Patients who initially survive the rupture and repair of a brain aneurysm often take a devastating turn for the worse some days later and die or suffer permanent neurologic deficits....