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Lars Demmel

Explore the profile of Lars Demmel including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 210
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Recent Articles
1.
Demmel L, Schmidt K, Lucast L, Havlicek K, Zankel A, Koestler T, et al.
J Cell Sci . 2016 Jun; 129(11):2285. PMID: 27252358
No abstract available.
2.
Demmel L, Schmidt K, Lucast L, Havlicek K, Zankel A, Koestler T, et al.
J Cell Sci . 2014 Mar; 127(Pt 10):2351-64. PMID: 24639465
Phosphoinositides are spatially restricted membrane signaling molecules. Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]--a phosphoinositide that is highly enriched in, and present throughout, the plasma membrane--has been implicated in endocytosis. Trypanosoma brucei has one...
3.
Sealey-Cardona M, Schmidt K, Demmel L, Hirschmugl T, Gesell T, Dong G, et al.
Traffic . 2014 Mar; 15(6):613-29. PMID: 24612401
The Sec16 homologue in Trypanosoma brucei has been identified and characterized. TbSec16 colocalizes with COPII components at the single endoplasmic reticulum exit site (ERES), which is next to the single...
4.
Morriswood B, Havlicek K, Demmel L, Yavuz S, Sealey-Cardona M, Vidilaseris K, et al.
Eukaryot Cell . 2012 Dec; 12(2):356-67. PMID: 23264645
The trypanosomes are a family of parasitic protists of which the African trypanosome, Trypanosoma brucei, is the best characterized. The complex and highly ordered cytoskeleton of T. brucei has been...
5.
Demmel L, Melak M, Kotisch H, Fendos J, Reipert S, Warren G
Traffic . 2011 Aug; 12(11):1575-91. PMID: 21801288
The Sec24 subunit of the coat protein complex II (COPII) has been implicated in selecting newly synthesized cargo from the endoplasmic reticulum (ER) for delivery to the Golgi. The protozoan...
6.
Demmel L, Gravert M, Ercan E, Habermann B, Muller-Reichert T, Kukhtina V, et al.
Mol Biol Cell . 2008 Feb; 19(5):1991-2002. PMID: 18287542
Phosphatidylinositol 4-phosphate (PI(4)P) is a key regulator of membrane transport required for the formation of transport carriers from the trans-Golgi network (TGN). The molecular mechanisms of PI(4)P signaling in this...
7.
Demmel L, Beck M, Klose C, Schlaitz A, Gloor Y, Hsu P, et al.
Mol Biol Cell . 2008 Jan; 19(3):1046-61. PMID: 18172025
The yeast phosphatidylinositol 4-kinase Pik1p is essential for proliferation, and it controls Golgi homeostasis and transport of newly synthesized proteins from this compartment. At the Golgi, phosphatidylinositol 4-phosphate recruits multiple...