Larry W Chamley
Overview
Explore the profile of Larry W Chamley including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
424
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Recent Articles
1.
Geng T, Tang M, Paek S, Leung E, Chamley L, Wu Z
Int J Pharm
. 2022 Sep;
626:122153.
PMID: 36055444
Small extracellular vesicles (sEVs) have emerged as attractive drug delivery systems. However, the intracellular release of their cargoes is restricted. This study aimed to develop an efficient approach to re-engineer...
2.
Boss A, Damani T, Wickman T, Chamley L, James J, Brooks A
Elife
. 2022 Aug;
11.
PMID: 35920626
Single-cell technologies (RNA-sequencing, flow cytometry) are critical tools to reveal how cell heterogeneity impacts developmental pathways. The placenta is a fetal exchange organ, containing a heterogeneous mix of mesenchymal cells...
3.
Tong M, Stanley J, Chen Q, James J, Stone P, Chamley L
Hum Reprod
. 2017 Oct;
32(11):2188-2198.
PMID: 29040541
Study Question: How do nano-vesicles extruded from normal first trimester human placentae affect maternal vascular function? Summary Answer: Placental nano-vesicles affect the ability of systemic mesenteric arteries to undergo endothelium-...
4.
Groom K, McCowan L, Mackay L, Lee A, Said J, Kane S, et al.
Am J Obstet Gynecol
. 2017 Feb;
216(3):296.e1-296.e14.
PMID: 28153659
Background: Preeclampsia and small-for-gestational-age pregnancy are major causes of maternal and perinatal morbidity and mortality. Women with a previous pregnancy affected by these conditions are at an increased risk of...
5.
Hammond E, McGillivray B, Wicker S, Peek J, Shelling A, Stone P, et al.
Fertil Steril
. 2016 Nov;
107(1):220-228.e5.
PMID: 27865449
Objective: To characterize nuclear and mitochondrial DNA (mtDNA) in spent culture media from normally developing blastocysts to determine whether it could be used for noninvasive genetic assessment. Design: Prospective embryo...
6.
Tong M, Kleffmann T, Pradhan S, Johansson C, DeSousa J, Stone P, et al.
Hum Reprod
. 2016 Feb;
31(4):687-99.
PMID: 26839151
Study Question: What proteins are carried by extracellular vesicles (EVs) released from normal first trimester placentae? Summary Answer: One thousand five hundred and eighty-five, 1656 and 1476 proteins were characterized...
7.
Mulla M, Salmon J, Chamley L, Brosens J, Boeras C, Kavathas P, et al.
PLoS One
. 2013 Jun;
8(6):e65237.
PMID: 23762324
Women with antiphospholipid syndrome (APS) are at risk of recurrent pregnancy loss and obstetrical disorders, such as preeclampsia and intrauterine growth restriction (IUGR). Antiphospholipid antibodies (aPL) directly target the placenta...
8.
Antony J, Oback F, Chamley L, Oback B, Laible G
Mol Cell Biol
. 2012 Dec;
33(5):974-83.
PMID: 23263990
Correct reprogramming of epigenetic marks in the donor nuclei is crucial for successful cloning by nuclear transfer. Specific epigenetic modifications, such as repressive histone lysine methylation marks, are known to...
9.
Odiari E, Mulla M, Sfakianaki A, Paidas M, Stanwood N, Gariepy A, et al.
Hum Reprod
. 2012 Aug;
27(10):2933-40.
PMID: 22888169
Study Question: What is the effect of pravastatin on antiphospholipid antibody (aPL) modulation of human first trimester trophoblast function? Summary Answer: Pravastatin does not prevent the effects of aPL on...
10.
Holland O, Linscheid C, Hodes H, Nauser T, Gilliam M, Stone P, et al.
Am J Pathol
. 2011 Nov;
180(1):256-66.
PMID: 22079431
The fetal semi-allograft can induce expansion and tolerance of antigen-specific maternal T and B cells through paternally inherited major histocompatibility complex and minor histocompatibility antigens (mHAgs). The effects of these...