Larry A Donehower
Overview
Explore the profile of Larry A Donehower including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
235
Followers
0
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Recent Articles
1.
Reddy J, Peddibhotla S, Bu W, Zhao J, Haricharan S, Du Y, et al.
Proc Natl Acad Sci U S A
. 2010 Feb;
107(8):3728-33.
PMID: 20133707
p53, apoptosis, and senescence are frequently activated in preneoplastic lesions and are barriers to progression to malignancy. These barriers have been suggested to result from an ATM-mediated DNA damage response...
2.
Bulavin D, Phillips C, Nannenga B, Timofeev O, Donehower L, Anderson C, et al.
Nat Genet
. 2004 Mar;
36(4):343-50.
PMID: 14991053
Modulation of tumor suppressor activities may provide new opportunities for cancer therapy. Here we show that disruption of the gene Ppm1d encoding Wip1 phosphatase activated the p53 and p16 (also...
3.
Biggs P, Vogel H, Sage M, Martin L, Donehower L, Bradley A
Oncogene
. 2003 May;
22(21):3288-96.
PMID: 12761499
Most tumour suppressor genes (TSGs) have been found through linkage studies in cancer predisposed families where the mutations have a high penetrance, for example, the breast cancer genes BRCA1 and...