Larissa E Hillebrand
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Explore the profile of Larissa E Hillebrand including associated specialties, affiliations and a list of published articles.
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6
Citations
61
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Recent Articles
1.
Decker T, Zaiss M, Klein D, Hahn A, Hagen V, La Rosee P, et al.
Breast Care (Basel)
. 2024 Feb;
19(1):49-61.
PMID: 38384487
Background: We investigated the efficacy and health-related quality of life (HRQoL) in patients receiving either ribociclib plus endocrine therapy (ET) or chemotherapy with/without bevacizumab as first-line treatment of metastatic hormone...
2.
Hillebrand L, Reinheckel T
Biochimie
. 2019 Mar;
166:214-222.
PMID: 30876968
Cancer cells within a tumor are heterogeneous and exist in a variety of functionally distinct cell states, which are thought to be hierarchically organized. The cell on top of this...
3.
Hillebrand L, Wickberg S, Gomez-Auli A, Follo M, Maurer J, Busch H, et al.
FASEB J
. 2018 Dec;
33(3):4124-4140.
PMID: 30521382
Tumor-initiating cells (TICs) existing in breast cancer are thought to be involved in initiation, progression, and relapse of tumors. In these processes, the epithelial-to-mesenchymal transition (EMT) and proteases are crucial...
4.
Ketterer S, Gomez-Auli A, Hillebrand L, Petrera A, Ketscher A, Reinheckel T
FEBS J
. 2016 Dec;
284(10):1437-1454.
PMID: 27926992
Lysosomal cathepsins are proteolytic enzymes increasingly recognized as prognostic markers and potential therapeutic targets in a variety of diseases. In those conditions, the cathepsins are mostly overexpressed, thereby driving the...
5.
Hillebrand L, Bengsch F, Hochrein J, Hulsdunker J, Bender J, Follo M, et al.
Oncotarget
. 2016 Aug;
7(36):58244-58260.
PMID: 27542270
Tumor initiating cells (TICs) have been identified and functionally characterized in hematological malignancies as well as in solid tumors such as breast cancer. In addition to their high tumor-initiating potential,...
6.
Tholen M, Hillebrand L, Tholen S, Sedelmeier O, Arnold S, Reinheckel T
Nat Commun
. 2014 Sep;
5:4931.
PMID: 25222295
The lysosomal protease cathepsin L has been reported to cleave various functionally important cytosolic or nuclear proteins. To explain nucleo-cytosolic localization of cathepsin L, it has been hypothesized that skipping...