Lance D Dworkin
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Explore the profile of Lance D Dworkin including associated specialties, affiliations and a list of published articles.
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68
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1661
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Recent Articles
1.
Gupta R, Estrella M, Scherzer R, Brewster P, Dworkin L, Nguyen H, et al.
Kidney Med
. 2025 Feb;
7(2):100948.
PMID: 39895851
Rationale & Objective: Although renal artery stenosis (RAS) and heart failure (HF) have been linked, the incidence and predictors of HF among patients with RAS are not well described. Study...
2.
Chen B, Chen M, Chang M, Ge Y, Gunning W, Assaly R, et al.
Kidney Int
. 2025 Jan;
PMID: 39862971
Melanocortin therapeutics, exemplified by adrenocorticotropic hormone, have a proven steroidogenic-independent anti-proteinuric and glomerular protective effect. The biological functions of melanocortins are mediated by melanocortin receptors (MCR), including MC1R, which recent...
3.
Breidenbach J, French B, Stanoszek L, Lavik J, Maddipati K, Premathilaka S, et al.
Toxins (Basel)
. 2024 Nov;
16(11).
PMID: 39591225
Harmful algal blooms are increasing globally and pose serious health concerns releasing cyanotoxins. Microcystin-LR (MC-LR), one of the most frequently produced cyanotoxins, has recently been detected in aerosols generated by...
4.
Arnold S, Wang K, Kirtane A, Magnuson E, Chinnakondepalli K, Cooper C, et al.
Eur Heart J Qual Care Clin Outcomes
. 2024 Oct;
PMID: 39402005
Background: Renal-artery stenosis can be associated with difficult to control hypertension, although renal-artery stenting has not been shown to improve clinical outcomes. Alternative antihypertensive medications could potentially result in quality...
5.
Dube P, Aradhyula V, Lad A, Khalaf F, Breidenbach J, Kashaboina E, et al.
Int J Mol Sci
. 2023 Jun;
24(12).
PMID: 37373209
Diet-induced models of chronic kidney disease (CKD) offer several advantages, including clinical relevance and animal welfare, compared with surgical models. Oxalate is a plant-based, terminal toxic metabolite that is eliminated...
6.
Didier A, Stiene J, Fang L, Watkins D, Dworkin L, Creeden J
Antioxidants (Basel)
. 2023 Mar;
12(3).
PMID: 36978880
Oxidative stress, a condition characterized by an imbalance between pro-oxidant molecules and antioxidant defense systems, is increasingly recognized as a key contributor to cancer development. This is because the reactive...
7.
Vellani S, Nigro A, Varatharajan S, Dworkin L, Creeden J
Molecules
. 2023 Mar;
28(5).
PMID: 36903295
Evasion of innate immunity represents a frequently employed method by which tumor cells survive and thrive. Previously, the development of immunotherapeutic agents capable of overcoming this evasion has realized pronounced...
8.
Modrall J, Zhu H, Prasad T, Moe O, Dworkin L, Cutlip D, et al.
J Vasc Surg
. 2023 Feb;
77(6):1685-1692.e2.
PMID: 36736864
Objective: The Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) trial, a multicenter randomized controlled trial with 947 patients, concluded that there was no benefit of renal artery stenting (RAS) over...
9.
Chen B, Guan X, Gunning W, Ge Y, Gohara A, Dworkin L, et al.
J Am Soc Nephrol
. 2022 Nov;
34(3):467-481.
PMID: 36446431
Significance Statement: Emerging evidence suggests that melanocortin neuropeptides-specifically adrenocorticotropic hormone-offer a novel, steroidogenic-independent therapeutic modality for membranous nephropathy (MN). The molecular mechanism underlying this beneficial effect, however, remains largely elusive....
10.
Guan X, Chen B, Malhotra D, Gohara A, Dworkin L, Gong R
Kidney Int
. 2022 Nov;
103(2):331-342.
PMID: 36374665
The melanocortin hormone system has emerged as a novel therapeutic target for treating refractory glomerular diseases. However, the role of hematopoietic melanocortin 1 receptor (MC1R) signaling remains unknown. Upon insult...