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Laina N Hall

Explore the profile of Laina N Hall including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 47
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Recent Articles
1.
Ghosh S, Wu C, Moller A, Launay A, Hall L, Hansen B, et al.
Nat Commun . 2025 Feb; 16(1):2067. PMID: 40021638
Bacterial pathogens can undergo striking adaptive evolutionary change in the context of infection, driven by selection forces associated with host defenses and antibiotic treatment. In this work, we analyze the...
2.
Prywes N, Phillips N, Oltrogge L, Lindner S, Taylor-Kearney L, Tsai Y, et al.
Nature . 2025 Feb; 638(8052):E47. PMID: 39930266
No abstract available.
3.
Prywes N, Phillips N, Oltrogge L, Lindner S, Taylor-Kearney L, Tsai Y, et al.
Nature . 2025 Jan; 638(8051):823-828. PMID: 39843747
Rubisco is the primary CO-fixing enzyme of the biosphere, yet it has slow kinetics. The roles of evolution and chemical mechanism in constraining its biochemical function remain debated. Engineering efforts...
4.
Prywes N, Philips N, Oltrogge L, Lindner S, Tsai Y, de Pins B, et al.
bioRxiv . 2024 Apr; PMID: 38645011
Rubisco is the primary CO fixing enzyme of the biosphere yet has slow kinetics. The roles of evolution and chemical mechanism in constraining the sequence landscape of rubisco remain debated....
5.
Nemudraia A, Nemudryi A, Buyukyoruk M, Scherffius A, Zahl T, Wiegand T, et al.
Nat Commun . 2022 Dec; 13(1):7762. PMID: 36522348
Type-III CRISPR-Cas systems have recently been adopted for sequence-specific detection of SARS-CoV-2. Here, we repurpose the type III-A CRISPR complex from Thermus thermophilus (TtCsm) for programmable capture and concentration of...
6.
Santiago-Frangos A, Hall L, Nemudraia A, Nemudryi A, Krishna P, Wiegand T, et al.
Cell Rep Med . 2021 Jun; 2(6):100319. PMID: 34075364
There is an urgent need for inexpensive new technologies that enable fast, reliable, and scalable detection of viruses. Here, we repurpose the type III CRISPR-Cas system for sensitive and sequence-specific...