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Lai-Jian Wang

Explore the profile of Lai-Jian Wang including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 95
Followers 0
Related Specialties
Biomedical Engineering
Biology
Neurology
Top 10 Co-Authors
Yuan-Shan Zeng
Bin Jiang
Xiang Zeng
Bi-Qin Lai
Ge Li
Ya-Qiong Wang
Ming-Tian Che
Yuan-Huan Ma
Ying Ding
Bo Feng
Published In
Biomaterials
Adv Sci (Weinh)
CNS Neurosci Ther
Sci Adv
Stem Cell Reports
Affiliations
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Recent Articles
1.
IPAC integrates rewarding and environmental memory during the acquisition of morphine CPP
Liu H, Liao M, Liu G, Wang L, Lian D, Ren J, et al.
Sci Adv . 2023 Jun; 9(25):eadg5849. PMID: 37352353
The association between rewarding and drug-related memory is a leading factor for the formation of addiction, yet the neural circuits underlying the association remain unclear. Here, we showed that the...
2.
Tail nerve electrical stimulation promoted the efficiency of transplanted spinal cord-like tissue as a neuronal relay to repair the motor function of rats with transected spinal cord injury
Lai B, Wu R, Han W, Bai Y, Liu J, Yu H, et al.
Biomaterials . 2023 Apr; 297:122103. PMID: 37028111
Following transected spinal cord injury (SCI), there is a critical need to restore nerve conduction at the injury site and activate the silent neural circuits caudal to the injury to...
3.
Electroacupuncture facilitates the integration of a grafted TrkC-modified mesenchymal stem cell-derived neural network into transected spinal cord in rats via increasing neurotrophin-3
Yang Y, Xu H, Deng Q, Wu G, Zeng X, Jin H, et al.
CNS Neurosci Ther . 2021 Mar; 27(7):776-791. PMID: 33763978
Aims: This study was aimed to investigate whether electroacupuncture (EA) would increase the secretion of neurotrophin-3 (NT-3) from injured spinal cord tissue, and, if so, whether the increased NT-3 would...
4.
Tissue-Engineered Neural Network Graft Relays Excitatory Signal in the Completely Transected Canine Spinal Cord
Lai B, Che M, Feng B, Bai Y, Li G, Ma Y, et al.
Adv Sci (Weinh) . 2019 Nov; 6(22):1901240. PMID: 31763143
Tissue engineering produces constructs with defined functions for the targeted treatment of damaged tissue. A complete spinal cord injury (SCI) model is generated in canines to test whether in vitro...
5.
Electroacupuncture Facilitates the Integration of Neural Stem Cell-Derived Neural Network with Transected Rat Spinal Cord
Jin H, Zhang Y, Yang Y, Wen L, Wang J, Xu H, et al.
Stem Cell Reports . 2019 Jan; 12(2):274-289. PMID: 30661994
The hostile environment of an injured spinal cord makes it challenging to achieve higher viability in a grafted tissue-engineered neural network used to reconstruct the spinal cord circuit. Here, we...
6.
A Modular Assembly of Spinal Cord-Like Tissue Allows Targeted Tissue Repair in the Transected Spinal Cord
Lai B, Feng B, Che M, Wang L, Cai S, Huang M, et al.
Adv Sci (Weinh) . 2018 Sep; 5(9):1800261. PMID: 30250785
Tissue engineering-based neural construction holds promise in providing organoids with defined differentiation and therapeutic potentials. Here, a bioengineered transplantable spinal cord-like tissue (SCLT) is assembled in vitro by simulating the...
7.
Recovery of paralyzed limb motor function in canine with complete spinal cord injury following implantation of MSC-derived neural network tissue
Wu G, Shi H, Che M, Huang M, Wei Q, Feng B, et al.
Biomaterials . 2018 Aug; 181:15-34. PMID: 30071379
We have reported previously that bone marrow mesenchymal stem cell (MSC)-derived neural network scaffold not only survived in the injury/graft site of spinal cord but also served as a "neuronal...