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L Zema

Explore the profile of L Zema including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 144
Followers 0
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Recent Articles
1.
Inverardi N, Scalet G, Melocchi A, Uboldi M, Maroni A, Zema L, et al.
J Mech Behav Biomed Mater . 2021 Sep; 124:104814. PMID: 34534845
The present paper aims at developing an integrated experimental/computational approach towards the design of shape memory devices fabricated by hot-processing with potential for use as gastroretentive drug delivery systems (DDSs)...
2.
Melocchi A, Inverardi N, Uboldi M, Baldi F, Maroni A, Pandini S, et al.
Int J Pharm . 2019 Feb; 559:299-311. PMID: 30707934
The use of shape memory polymers exhibiting water-induced shape recovery at body temperature and water solubility was proposed for the development of indwelling devices for intravesical drug delivery. These could...
3.
Casati F, Briatico-Vangosa F, Baldi F, Melocchi A, Maroni A, Gazzaniga A, et al.
Int J Pharm . 2018 Jul; 548(1):400-407. PMID: 29981413
The present work focuses on application of an investigational approach to assess the hot-processability of pharmaceutical-grade polymers with a potential for use in the manufacturing of reservoir drug delivery systems...
4.
Maroni A, Melocchi A, Parietti F, Foppoli A, Zema L, Gazzaniga A
J Control Release . 2017 Oct; 268:10-18. PMID: 29030223
In the drug delivery area, versatile therapeutic systems intended to yield customized combinations of drugs, drug doses and release kinetics have drawn increasing attention, especially because of the advantages that...
5.
Macchi E, Zema L, Maroni A, Gazzaniga A, Felton L
Eur J Pharm Sci . 2015 Jan; 70:1-11. PMID: 25585355
Capsular devices based on hydroxypropyl cellulose (Klucel® LF) intended for pulsatile release were prepared by injection molding (IM). In the present work, the possibility of exploiting such capsules for the...
6.
Di Pretoro G, Zema L, Palugan L, Wilson D, Rough S, Gazzaniga A
Eur J Pharm Sci . 2011 Nov; 45(1-2):158-68. PMID: 22108344
Pellets with high loading of 5-aminosalicylic acid (5-ASA, mesalamine) are desired to reduce the number of tablets required to deliver the daily dosing regimen. Recently, we reported an extrusion-spheronisation route...
7.
Di Pretoro G, Zema L, Gazzaniga A, Rough S, Wilson D
Int J Pharm . 2010 Oct; 402(1-2):153-64. PMID: 20934502
The aim of the current work was to develop an extrusion-spheronisation (E-S) route to manufacture pellets with a high loading (≥90wt%) of 5-aminosalicylic acid (5-ASA). Ram extrusion studies, supported by...
8.
Zema L, Sangalli M, Maroni A, Foppoli A, Bettero A, Gazzaniga A
Eur J Pharm Biopharm . 2010 Mar; 75(2):291-6. PMID: 20304050
A delivery device intended for the prolonged release of antimicrobial agents, able to enhance the stability profile of liquid/semi-solid cosmetic/pharmaceutical products for topical application, was proposed in the present study....
9.
Zema L, Maroni A, Foppoli A, Palugan L, Sangalli M, Gazzaniga A
J Pharm Sci . 2006 Nov; 96(6):1527-36. PMID: 17094127
When used as release-controlling coating agents for tableted core-based pulsatile delivery systems, three different hydroxypropyl methylcellulose (HPMC) grades, Methocel E5, E50, and K4M, provided lag phases of varying duration (Methocel...
10.
Sangalli M, Maroni A, Foppoli A, Zema L, Giordano F, Gazzaniga A
Eur J Pharm Sci . 2004 Jul; 22(5):469-76. PMID: 15265517
Currently, delayed/pulsatile release and colon delivery represent topics of remarkable interest. The present paper deals with the study and development of an oral dosage form devised to release drugs following...