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L W M M Terstappen

Explore the profile of L W M M Terstappen including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 1127
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Recent Articles
1.
Rikkert L, Beekman P, Caro J, Coumans F, Enciso-Martinez A, Jenster G, et al.
Front Oncol . 2020 Jun; 10:608. PMID: 32582525
Extracellular vesicles (EVs) have great potential as biomarkers since their composition and concentration in biofluids are disease state dependent and their cargo can contain disease-related information. Large tumor-derived EVs (tdEVs,...
2.
Andree K, Mentink A, Nguyen A, Goldsteen P, van Dalum G, Broekmaat J, et al.
Lab Chip . 2019 Feb; 19(6):1006-1012. PMID: 30762848
The load of circulating tumor cells (CTC) is related to poor outcomes in cancer patients. A sufficient number of these cells would enable a full characterization of the cancer. An...
3.
Rikkert L, Nieuwland R, Terstappen L, Coumans F
J Extracell Vesicles . 2019 Jan; 8(1):1555419. PMID: 30651939
Transmission electron microscopy (TEM) has nanometre resolution and can be used to distinguish single extracellular vesicles (EVs) from non-EV particles. TEM images of EVs are a result of operator image...
4.
Enciso-Martinez A, Timmermans F, Nanou A, Terstappen L, Otto C
Analyst . 2018 Aug; 143(18):4495-4502. PMID: 30160261
Correlative and integrated scanning electron microscopy (SEM) and Raman micro-spectroscopy is presented that enables the characterization and identification of different cancer and non-cancer cells through SEM-Raman image cytometry. The hybrid...
5.
Lorente D, Olmos D, Mateo J, Dolling D, Bianchini D, Seed G, et al.
Ann Oncol . 2018 May; 29(7):1554-1560. PMID: 29741566
Background: The development of treatment response and surrogate biomarkers for advanced prostate cancer care is an unmet clinical need. Patients with baseline circulating tumour cell (BLCTCs) counts <5/7.5 mL represent...
6.
Abali F, Stevens M, Tibbe A, Terstappen L, van der Velde P, Schasfoort R
Anal Biochem . 2017 May; 531:45-47. PMID: 28545866
Here the feasibility is demonstrated that by combining Surface Plasmon Resonance Imaging (SPRi) and self-sorting microwell technology product secretion of individual cells can be monitored. Additionally isolation of the selected...
7.
Swennenhuis J, van Dalum G, Zeune L, Terstappen L
Expert Rev Mol Diagn . 2016 Nov; 16(12):1291-1305. PMID: 27797592
The CellSearch® CTC test enumerates tumor cells present in 7.5 ml blood of cancer patients. improvements, extensions and different utilities of the cellsearch system are discussed in this paper. Areas...
8.
Crespo M, van Dalum G, Ferraldeschi R, Zafeiriou Z, Sideris S, Lorente D, et al.
Br J Cancer . 2015 Feb; 112(7):1166-74. PMID: 25719830
Background: Abiraterone and enzalutamide are novel endocrine treatments that abrogate androgen receptor (AR) signalling in castration-resistant prostate cancer (CRPC). Here, we developed a circulating tumour cells (CTCs)-based assay to evaluate...
9.
Vanna R, Ronchi P, Lenferink A, Tresoldi C, Morasso C, Mehn D, et al.
Analyst . 2015 Jan; 140(4):1054-64. PMID: 25568900
In clinical practice, the diagnosis and classification of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) start from the manual examination of stained smears of bone marrow (BM) and peripheral...
10.
Ligthart S, Bidard F, Decraene C, Bachelot T, Delaloge S, Brain E, et al.
Ann Oncol . 2013 Jan; 24(5):1231-8. PMID: 23275633
Background Circulating tumor cells (CTCs) can provide the basis for a liquid biopsy and may guide the use of targeted therapies. We report on unbiased quantification of Her-2 protein expression...